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. 2025 Jun 26;16:100189. doi: 10.1016/j.obpill.2025.100189

Table 2.

Main findings of studies on long-term interventions in children.

References Study Design Population and methods Main findings
[40] Parallel RCT
Duration: 24 weeks
N = 322 (EG n = 160, CG = 162)
Children with overweight or obesity aged 10–14 years, regularly using sedentary video games
Intervention: active video game to play at home.
Subgroup analysis (baseline outcome, age, sex, and ethnicity)
At 24 weeks, significant differences for BMI, BMI Z-score, and body fat percentage were found in EG vs. CG.
No statistically significant interactions were observed between the treatment and any subgroups across all regression models (p = 0.36 to 0.93).
[41] Group-RCT
Duration: 6 months
N = 64 (intervention n = 32, control n = 32)
Male children, between 9 and 10 years old, from an elementary school in Italy
Intervention: 45 min exergaming sessions (Kinect Adventures) 3 times a week
+ supplementary physical activity outside the regular school program
BMI (-1.6 in EG vs 0 in CG), body weight (-2.3 in EG vs +1 in CG), and relative fat mass, (-1.7 in EG vs, +0.5 in CG) showed a significant reduction (all p ​< ​0.001).
Significant improvement of aerobic fitness (+80.51 ​± ​10.66 ​m in EG, p ​= ​0.004 vs ​+ ​10.4 2.59 ​m in CG, p ​= ​0.485) and flexibility (+75 ​% in EG vs ​+ ​28 ​% in CG (p ​< ​0.001) was observed.
No significant improvement in standing long jump test was found (150.20 ± 6.1 cm in EG vs 149.92 ± 6.8 cm in CG, p > 0.05).
No sustained children enjoyment after 20 weeks.
[43] Longitudinal observational multicenter study.
Duration: 6 months.
N = 357 adolescents (13–16 years) from 4 European countries (Italy, UK, Spain, Netherlands)
Mobile app “e-Diary” for real-time food tracking, gamification features, notifications, personalized suggestions, visual feedback and dietary indices.
Both fruit and vegetable intake significantly increased (p < 0.0001 and p = 0.0087, respectively)
Adolescents with app usage >2 weeks demonstrated significantly higher odds of breakfast consumption adherence over the study duration (aOR 2.5, 95 % CI 1.0–6.3).
A higher engagement among females (aOR 3.8, 95 % CI 1.6–8.8), participants 14-year-olds (aOR 5.1, 95 % CI 1.4–18.8), and adolescents with self-reported good health (aOR 4.2, 95 % CI 1.3–13.3) was found.

Abbreviations: aOR, adjusted odds ratio; BMI, body mass index; CG: control group; EG: experimental group; RCT, Randomized controlled trial.