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. 2025 Jun 26;11:101127. doi: 10.1016/j.crfs.2025.101127

Table 3b.

Model results.

Name Acc NER F1 Pr ROC AUC PR AUC R MCC Sn Sp R2 RMSE
SMILES to Smell: Decoding the Structure–Odor Relationship of Chemical Compounds Using the Deep Neural Network Approach (Sharma et al., 2021b) 0.98 0.88 0.97 micro avg: 0.87 macro avg: 0.7 micro avg: 0.74 macro avg: 0.75 0.84
Predicting odor from vibrational spectra: a data-driven approach (Ameta et al., 2024) 0.41 0.36 0.47
Predicting natural language descriptions of mono-molecular odorants (Gutiérrez et al., 2018) 0.66
A principal odor map unifies diverse tasks in olfactory perception (Lee et al., 2023) 0.89∗
Odor Impression Prediction from Mass Spectra (Nozaki and Nakamoto, 2016) 0.76∗
Application of artificial intelligence to decode the relationships between smell, olfactory receptors and small molecules (Achebouche et al., 2022)
 odor note: 0.82∗ 0.24∗
 odor group: 0.80∗ 0.40∗
XGBoost odor prediction model: finding the structure-odor relationship of odorant molecules using the extreme gradient boosting algorithm (Tyagi et al., 2024) 0.99 0.99 0.99 0.99 0.99 0.99 0.99
Predictive modeling for odor character of a chemical using machine learning combined with natural language processing (Nozaki and Nakamoto, 2018) 0.69∗ 0.63∗ 0.78∗ 0.40∗ 0.53∗ 0.85∗
iBitter-SCM: Identification and characterization of bitter peptides using a scoring card method with propensity scores of dipeptides (Charoenkwan et al., 2020a) 0.84 0.90 0.69 0.84 0.84
e-Bitter: Bitterant Prediction by the Consensus Voting From the Machine-Learning Methods (Zheng et al., 2018) 0.93 0.94 0.92 0.86 0.95 0.90
BitterX: a tool for understanding bitter taste in humans (Huang et al., 2016) 0.92 0.91 0.96 0.94 0.91
Bitter or not? BitterPredict, a tool for predicting taste from chemical structure (Dagan-Wiener et al., 2017) 0.83 0.77 0.86
BERT4Bitter: a bidirectional encoder representations from transformers (BERT)-based model for improving the prediction of bitter peptides (Charoenkwan et al., 2021a) 0.92 0.96 0.84 0.94 0.91
iBitter-Fuse: A Novel Sequence-Based Bitter Peptide Predictor by Fusing Multi-View Features (Charoenkwan et al., 2021c) 0.93 0.93 0.86 0.94 0.92
Prediction of bitterant and sweetener using structure-taste relationship models based on an artificial neural network (Bo et al., 2022) 0.88 0.89 0.95 0.75 0.83 0.93
Novel scaffold of natural compound eliciting sweet taste revealed by machine learning (Bouysset et al., 2020) 0.75
Sweetness prediction of natural compounds (Chéron et al., 2017b) 0.85
A QSTR-Based Expert System to Predict Sweetness of Molecules (Rojas et al., 2017) 0.85 0.88 0.82
Machine learning models to predict sweetness of molecules (Goel et al., 2023) 0.94 0.33
VirtualTaste: a web server for the prediction of organoleptic properties of chemical compounds (Fritz et al., 2021)
 sweet: 0.89 0.88 0.95 0.68 0.92
 bitter: 0.90 0.88 0.96 0.88 0.97
 sour: 0.97 0.84 0.99 0.80 0.99
Predicting multiple taste sensations with a multiobjective machine learning method (Androutsos et al., 2024) 0.72 0.74 0.79 0.87 0.72
BitterSweetForest: A Random Forest Based Binary Classifier to Predict Bitterness and Sweetness of Chemical Compounds (Banerjee and Preissner, 2018)
 sweet 0.97 0.92 0.98 0.91 0.97
 bitter 0.97 0.95 0.98 0.97 0.91
Informed classification of sweeteners/bitterants compounds via explainable machine learning (Maroni et al., 2022) 0.88∗ 0.87∗ 0.95∗ 0.94∗ 0.89∗
BitterSweet: Building machine learning models for predicting the bitter and sweet taste of small molecules (Tuwani et al., 2019)
 sweet 0.83 0.86 0.88 0.95 0.79 0.88
 bitter 0.82 0.86 0.88 0.93 0.85 0.79
e-Sweet: A Machine-Learning Based Platform for the Prediction of Sweetener and Its Relative Sweetness (Zheng et al., 2019) 0.91 0.9 0.88 0.9 0.81 0.86 0.94 0.78 0.28
A Comprehensive Comparative Analysis of Deep Learning Based Feature Representations for Molecular Taste Prediction (Song et al., 2023)
 sweet 0.90 0.85 0.84 0.86 0.92
 bitter 0.89 0.87 0.93 0.82 0.95
 umami 0.99 0.91 1.00 0.84 1.00
BoostSweet: Learning molecular perceptual representations of sweeteners (Lee et al., 2022) 0.90 0.91 0.96 0.97 0.91 0.90
A novel multi-layer prediction approach for sweetness evaluation based on systematic machine learning modeling (Yang et al., 2022) 0.85 0.48
Toward a general and interpretable umami taste predictor using a multi-objective machine learning approach (Pallante et al., 2022) 0.88 0.79 0.85 0.79 0.92
iUmami-SCM: A Novel Sequence-Based Predictor for Prediction and Analysis of Umami Peptides Using a Scoring Card Method with Propensity Scores of Dipeptides (Charoenkwan et al., 2020b) 0.87 0.90 0.68 0.71 0.93
UMPred-FRL: A New Approach for Accurate Prediction of Umami Peptides Using Feature Representation Learning (Charoenkwan et al., 2021b) 0.82 0.91 0.56 0.57 0.93
Umami-BERT: An interpretable BERT-based model for umami peptides prediction (Zhang et al., 2023) 0.95∗ 0.97∗ 0.85∗ 0.97∗ 1.00∗
Umami-MRNN: Deep learning-based prediction of umami peptide using RNN and MLP (Qi et al., 2023) 0.93 0.97 0.86 0.97 0.91
Artificial neural networks modeling of non-fat yogurt texture properties: effect of process conditions and food composition (Batista et al., 2021)
 firmness 1.00∗∗ 0.00∗∗
 cohesiveness 1.00∗∗ 0.00∗∗
 adhesiveness 0.98∗∗ 0.00∗∗
 gumminess 1.00∗∗ 0.00∗∗
Predicting the Textural Properties of Plant-Based Meat Analogs with Machine Learning (Kircali Ata et al., 2023)
 hardness 10.10∗∗
 chewiness 6.04∗∗
Rapid and Non-Invasive Assessment of Texture Profile Analysis of Common Carp (Cyprinus carpio L.) Using Hyperspectral Imaging and Machine Learning (Cao et al., 2023) 32 targets, see paper for full results.
Prediction of textural characteristics in low-fat mozzarella cheese by Hyperspectral imaging using machine learning methods (Jahani et al., 2024)
 hardness 0.88∗∗
 adhesiveness 0.81∗∗
 springiness 0.85∗∗
 cohesiveness 0.70∗∗
 gumminess 0.82∗∗
 chewiness 0.84∗∗
Non-destructive prediction of texture of frozen/thaw raw beef by Raman spectroscopy (Chen et al., 2020)
 tenderness 0.81∗∗
 chewiness 0.80∗∗
 firmness 0.81∗∗
 hardness 0.82∗∗
 springiness 0.53∗∗
Prediction of textural changes in grass carp fillets as affected by vacuum freeze drying using hyperspectral imaging based on integrated group wavelengths (Ma et al., 2017)
WBSF 0.91∗∗
 hardness 0.90∗∗
 gumminess 0.88∗
 chewiness 0.90∗∗
Prediction of color, texture, and sensory characteristics of beef steaks by visible and near infrared reflectance spectroscopy. A feasibility study (Liu et al., 2003) 0.96∗∗
Rapid determination of the textural properties of silver carp (Hypophthalmichthys molitrix) using near-infrared reflectance spectroscopy and chemometrics (Zhou et al., 2020)
 WHC 0.95∗∗
 hardness 0.89∗∗
 resilience 0.87∗∗
 springiness 0.83∗∗
 chewiness 0.92∗∗
 shear force 0.88∗∗
Potential of hyperspectral imaging combined with chemometric analysis for assessing and visualising tenderness distribution in raw farmed salmon fillets (He et al., 2014)
 WBSF 0.90

The performance of all models listed in Table 3a. Metrics include accuracy (Acc), non-error rate (NER), F1 score, precision (Pr), area under the receiver operating characteristic curve (ROC AUC), R score, Matthews correlation coefficient (MCC), sensitivity (Sn), specificity (Sp), R2 score, and root mean squared error (RMSE).