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. Author manuscript; available in PMC: 2006 Mar 1.
Published in final edited form as: Blood. 2004 Sep 16;105(5):2016–2022. doi: 10.1182/blood-2004-05-1915

Figure 5.

Figure 5

Immunization of mice with 12B1-derived CRCL-loaded DCs provides superior therapeutic effects. BALB/c mice were injected with 3 × 103 12B1 cells subcutaneously in the right groin on day 0. On day 2, mice were immunized with 5 × 105 DCs that had been loaded with 12B1-derived CRCL or indicated peptides as mentioned in “Materials and methods.” Survival of mice was monitored and displayed in the Kaplan-Meier plot (n = 8–16 mice per group; pooled data from 2 experiments are shown). PBS versus DC/CRCL, P < .05; PBS versus DC/BCR-ABL peptide, P <.05; DC/irrelevant peptide versus DC/CRCL, P <.05; DC/irrelevant peptide versus DC/BCR-ABL peptide, P <.05; DC/CRCL versus DC/BCR-ABL, P <.05.