Table 3.

Cox proportional hazard ratios (HR) for all-cause mortality

	Model 1		Model 2		Model 3
	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
ICU mortality
ACAG (continuous)	1.06 (1.03–1.10)	< 0.001	1.06 (1.02–1.10)	0.002	1.07 (1.03–1.12)	< 0.001
Lower ACAG	Reference		Reference		Reference
Higher ACAG	2.69 (1.70–4.27)	< 0.001	2.66 (1.68–4.24)	< 0.001	2.62 (1.57–4.38)	< 0.001
In hospital mortality
ACAG (continuous)	1.07 (1.04–1.10)	< 0.001	1.08 (1.04–1.11)	< 0.001	1.07 (1.04–1.11)	< 0.001
Lower ACAG	Reference		Reference		Reference
Higher ACAG	2.66 (1.78–3.97)	< 0.001	2.84 (1.90–4.24)	< 0.001	2.61 (1.68–4.07)	< 0.001
14-day mortality
ACAG (continuous)	1.08 (1.04–1.12)	< 0.001	1.08 (1.05–1.12)	< 0.001	1.08 (1.03–1.12)	< 0.001
Lower ACAG	Reference		Reference		Reference
Higher ACAG	3.26 (2.09–5.10)	< 0.001	3.40 (2.17–5.32)	< 0.001	2.86 (1.70–4.80)	< 0.001
28-day mortality
ACAG (continuous)	1.07 (1.04–1.11)	< 0.001	1.08 (1.05–1.12)	< 0.001	1.07 (1.04–1.11)	< 0.001
Lower ACAG	Reference		Reference		Reference
Higher ACAG	3.01 (2.05–4.42)	< 0.001	3.17 (2.15–4.65)	< 0.001	2.78 (1.79–4.32)	< 0.001
90-day mortality
ACAG (continuous)	1.07 (1.04–1.10)	< 0.001	1.08 (1.05–1.11)	< 0.001	1.07 (1.04–1.10)	< 0.001
Lower ACAG	Reference		Reference		Reference
Higher ACAG	2.81 (2.03–3.92)	< 0.001	3.10 (2.22–4.32)	< 0.001	2.65 (1.81–3.87)	< 0.001

Model 1: Unadjusted;

Model 2: Adjusted age, gender, and ethnicity;

Model 3: Adjusted age, gender, ethnicity, serum creatinine, white blood cells, platelet, lactate, hypertension, heart failure, respiratory failure, diabetes, vasopressin, continuous renal replacement therapy, and Sequential Organ Failure Assessment