Table 1.

Generation, survival, and growth of ADH-deficient mice

Genotype	Litters	Pups born	Pups/litter	Postnatal mortality	% survival, no.	Weight at 14 weeks, g
WT	17	144	8.47  ± 0.47	1	99.3 (143)	34.3  ± 1.2
Adh1−/−	17	151	8.88  ± 0.49	7	95.4 (144)	34.4  ± 3.2
Adh3−/−	17	121	6.95  ± 0.51*	18	85.1 (103)**	24.7  ± 0.8**
Adh4−/−	17	166	9.76  ± 0.63	3	98.2 (163)	38.2  ± 3.4

All mice were propagated on standard mouse chow. Reported postnatal mortality occurred between birth and weaning (postnatal day 19); % survival refers to mice alive at weaning. Values are mean ± SE; for determination of body weight in 14-week-old male mice (n = 14). 

^*, P < 0.05; 

^**, P < 0.001 (Student's t test, Adh3^−/− vs. WT).