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. 2025 Apr 22;7(7):972–985. doi: 10.1016/j.cjco.2025.04.011

Table 3.

Readmission rates and in-hospital outcomes during readmission

Discharge to 30-d cohort All patients (n=16,004) Hospital Frailty Risk Score
Adjusted
P value
Low (n=7357) Intermediate (n=7163) High (n=1484)
Readmission data
 30-d readmission rate 2185 (14) 912 (12) 1111 (16) 162 (11) 0.001
 MAE during readmission 605 (28) 220 (24) 335 (30) 50 (31) 0.006
 Acute kidney injury 804 (37) 287 (31) 431 (39) 86 (53) <0.001
 Need for transfusions 296 (14) 120 (13) 151 (14) 25 (15) 0.57
 In-hospital death during readmission 179 (8.2) 71 (7.8) 84 (7.6) 24 (15) 0.09
 Length of stay (d) 4 (2-7) 4 (2-6) 4 (2-7) 5 (3-9) <0.001
 ≤4 d 1201 (55) 546 (60) 575 (52) 80 (49) 0.008
 >4 d 984 (45) 366 (40) 536 (48) 82 (51)
 Readmission cost (USD) 9775 (5457-19,886) 9088 (5129-19,789) 9987 (5740-19,463) 11,547 (6265-22,387) <0.001
Discharge destination after readmission
 Home (self-care) 774 (39) 424 (50) 319 (31) 31 (22) <0.001
 Short-term hospital 35 (1.7) 13 (1.5) 18 (1.8) <11 (2.9)
 Transfer to other institution 556 (28) 137 (16) 359 (35) 60 (43)
 Home health care 623 (31) 263 (31) 319 (31) 41 (30)
 Against medical advice 18 (0.9) <11 (0.5) 12 (1.2) <11 (1.4)

Discharge to 31-180-d cohort All patients (n=6497) Hospital Frailty Risk Score Adjusted
P value

Low (n=2976)
Intermediate (n=2898)
High (n=623)

Readmission data
 31-180-d readmission rate 1809 (28) 614 (21) 964 (33) 231 (37) <0.001
 MAE during readmission 201 (11) 65 (11) 105 (11) 31 (13) 0.59
 Acute kidney injury 585 (32) 159 (26) 338 (35) 88 (38) <0.001
 Need for transfusions 196 (11) 58 (9.4) 103 (11) 35 (15) 0.08
 In-hospital death during readmission 116 (6.4) 29 (4.7) 68 (7.1) 19 (8.2) 0.02
 Length of stay (d) 4 (2-8) 4 (2-6) 4 (3-8) 5 (3-9) <0.001
 ≤4 d 985 (54) 369 (60) 512 (53) 104 (45) <0.001
 >4 d 824 (46) 245 (40) 452 (47) 127 (55)
 Readmission cost (USD) 10,386 (5621-20,526) 10,128 (5297-20,200) 10,385 (5661-20,932) 10,921 (6786-21,333) <0.001
Discharge destination after readmission
 Home (self-care) 758 (45) 345 (59) 358 (40) 55 (26) <0.001
 Short-term hospital 18 (1.1) <11 (1.0) <11 (1.1) <11 (0.9)
 Transfer to other institution 434 (26) 92 (16) 255 (28) 87 (41)
 Home health care 473 (28) 137 (23) 269 (30) 67 (32)
 Against medical advice <11 (0.6) <11 (0.9) <11 (0.4) <11 (0.5)

Values are expressed as mean ± standard deviation, median (interquartile range), or counts (%) unless otherwise noted. Exact counts for variables with <11 patients are not detailed per the Healthcare Cost and Utilization Project data use agreement. Boldface indicates statistical significance (P < .05).

CI, confidence interval; MAE, major adverse events; OR, odds ratio; USD, US dollar.

Adjusted P values for each variable were computed from adjusting sampling design by discharge-level weights, cluster, and strata.

Other institutions included skilled nursing facilities, intermediate care, or other types of facilities not elsewhere included.