. 2025 Jul 14;16(33):14988–14994. doi: 10.1039/d5sc03007b

Table 2. Substrate scope of (Z)-isomer^a^,^b^,^c^,^d.

graphic file with name d5sc03007b-u3.jpg

Reaction conditions: 1 (0.3 mmol), B₂(pin)₂ (91 mg, 0.36 mmol), Cu(CH₃CN)₄PF₆ (2.8 mg, 2.5 mol%), (S,S)-Ph-BPE (7.6 mg, 5.0 mol%), ^tBuOH (57 μL, 0.6 mmol), LiO^tBu (54 μL, 0.6 mmol, 1.0 M THF solution), in THF solvent (3 mL, 0.1 M).

Isolated yields after column chromatography.

Enantiomeric ratio (er) was determined by chiral HPLC analysis.

>20 : 1 dr was observed (unless otherwise mentioned) through ¹H NMR analysis of a crude reaction mixture. SM = Starting material.

Table 2. Substrate scope of (Z)-isomera,b,c,d.

Table 2. Substrate scope of (Z)-isomer^a^,^b^,^c^,^d.