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. 2025 Jul 17;14(7):e250285. doi: 10.1530/EC-25-0285

Table 4.

Associations of serum IGFBP2, body composition, and metabolic variables with LSM.

Model 1 Model 2
r value P value r value P value
IGFBP2 (ng/mL) 0.059 0.272 0.069 0.202
BMI (kg/m2) 0.441 <0.001* −0.056 0.300
WHR (%) 0.290 <0.001* −0.013 0.807
VFA (cm2) 0.253 <0.001* −0.082 0.129
BFM (kg) 0.380 <0.001* −0.083 0.122
ALT (U/L) 0.380 <0.001* 0.290 <0.001*
AST (U/L) 0.435 <0.001* 0.329 <0.001*
GGT (U/L) 0.385 <0.001* 0.267 <0.001*
TC (mmol/L) 0.062 0.250 0.101 0.062
TG (mmol/L) 0.149 0.005* 0.096 0.074
HDL-C (mmol/L) −0.115 0.032* −0.061 0.256
LDL-C (mmol/L) 0.086 0.112 0.108 0.044*
FPG (mmol/L) 0.168 0.002* 0.173 0.001*
HbA1c (%) 0.237 <0.001* 0.195 <0.001*
FINS (mU/L) 0.395 <0.001* 0.231 <0.001*
HOMA-IR 0.401 <0.001* 0.251 <0.001*
HOMA-β 0.297 <0.001* 0.131 0.015*
UA (umol/L) 0.335 <0.001* 0.196 <0.001*

Note: Correlation analyses were conducted to examine the association between LSM and possible factors. Model 1: no variable adjustment (Pearson); Model 2: adjusted for age, height, and weight based on Model 1 (Partial). The parameters LSM, IGFBP2, VFA, BMI, WC, BFM, AST, ALT, GGT, TC, TG, HDL-C, FPG, HbA1c, FINS, HOMA-IR, HOMA-β, and UA, with a skewed distribution, underwent log(x) transformation to achieve a normal distribution before analysis.

*

Significance, P < 0.05.