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. 2002 Mar 26;99(8):5486–5491. doi: 10.1073/pnas.072626199

Figure 1.

Figure 1

Gene duplication and functional changes in the evolution of EDN and ECP genes of higher primates. The RNase activities shown are from the present study, except that of ECP, which was transformed from the originally reported value to reflect the activity expected under the present experimental conditions. Antiviral activities relative to that of human EDN are shown. For antibacterial activity, + and − indicate activity detected or undetected. MY, million year (7, 22–24, 26, 27, 31, 33).