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. Author manuscript; available in PMC: 2025 Jul 22.
Published in final edited form as: Med Mycol. 2025 Jun 5;63(6):myaf049. doi: 10.1093/mmy/myaf049

Table 2:

Total economic burden* of fungal diseases, United States

Indirect costs due to productivity loss
Disease Total direct medical costs From workdays lost due to hospitalizations From workdays lost due to outpatient visits From premature deaths Total economic burden
Aspergillosis $2,028,442,227 $101,596,045 $3,568,606 $615,165,702 $2,748,772,580
Blastomycosis $82,975,143 $5,918,846 $4,398,263 $49,777,981 $143,070,232
Candida infection $4,259,657,979 $291,966,352 $235,022,700 $1,104,396,539 $5,891,043,570
Invasive or severe candidiasis $4,329,051,014 $284,760,493 $6,466,774 $656,950,542 $5,277,228,824
Non-invasive/unspecified candidiasis $1,008,652,811 $3,917,419 $260,796,154 $376,100,073 $1,649,466,457
Coccidioidomycosis $645,919,784 $46,493,269 $54,023,590 $141,941,614 $888,378,257
Cryptococcosis $370,489,540 $33,590,311 $983,997 $304,575,033 $709,638,882
Dermatophytosis (ringworm) and other superficial mycoses $1,270,737,246 $629,810 $653,414,214 $1,924,781,270
Histoplasmosis $299,994,242 $22,080,742 $49,253,393 $132,505,839 $503,834,216
Pneumocystis pneumonia $679,408,224 $55,481,945 $1,124,735 $482,296,135 $1,218,311,039
Mucormycosis $622,042,667 $16,075,282 $563,981 $197,982,608 $836,664,537
Other and unspecified mycoses $3,107,315,255 $130,654,240 $5,601,278 $1,257,746,774 $4,501,317,546
Total $13,366,982,307 $704,486,842 $1,007,954,756 $4,286,388,225 $19,365,812,130
*

In 2024 dollars.

Not calculated because no in-hospital deaths due to dermatophytosis occurred.