Table 1.
Group | Donor type† | Odor source | Gender |
N (per
panel)*
|
Age range,
weeks‡
|
||||
---|---|---|---|---|---|---|---|---|---|
Training
|
Generalization
|
||||||||
+ | − | + | − | + | − | ||||
1 | Infectious MMTV | Mice | Female | 16 | 19 | 12 | 12 | 12–32 | 12–32 |
2 | Infectious MMTV | Urine | Female | 34 | 38 | 14 | 14 | 12–36 | 12–36 |
3 | Infectious MMTV | Mice | Male | 20 | 12 | 12 | 12 | 12–32 | 12–32 |
4 | Infectious MMTV | Urine | Male | 34 | 38 | 32 | 24 | 12–32 | 12–32 |
5 | Rederived infectious MMTV | Mice | Female | 24 | 24 | 12 | 12 | 12–40 | 12–40 |
6 | Rederived infectious MMTV | Urine | Female | 44 | 42 | 12 | 13 | 20–44 | 20–44 |
+/− | −/− | +/− | −/− | +/− | −/− | ||||
7 | Genetically transmitted MMTV | Urine | Male | 13 | 4 | 10 | 11 | 16–24 | 20–24 |
Number of individual mice making up each donor panel. For any given trial, one mouse or urines of one to three mice selected randomly from the donor panel served as the stimulus. +, mice positive for infectious MMTV; −, mice without infectious MMTV; +/−, mice heterozygous for MMTV provirus; −/−, mice with no MMTV provirus alleles.
Infectious MMTV, MMTV transmitted from mother to offspring via virus particles in mouse milk. Rederived infectious MMTV, offspring of previously noninfected female mice fostered onto infected nursing mothers. Genetically transmitted MMTV, mice carrying an endogenous MMTV provirus.
Post hoc examination of the data showed no indication of any differences in response as a function of age of donors.