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. 2025 Jun 27;10(7):e00282-25. doi: 10.1128/msystems.00282-25

Fig 1.

The diagram presents the agr operon with mutations in agrC and agrA and the quorum sensing pathway involving AgrD processing, AIP signaling, AgrC-AgrA phosphorylation, RNA3 activation, and regulation of virulence and surface protein expression.

(A) Accessory gene regulator (agr) system mutations in N08CSA36 and N09HSA31.1 represent the mutation in N08CSA36, and two represent the mutation in N09HSA31. (B) Molecular structure, signal synthesis, and transduction cascade of the agr quorum sensing system.