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Proposed functional roles for Ech and ferredoxin during growth of M. barkeri on various substrates. Models for growth on methanol plus H2/CO2 (A), acetate (B), H2/CO2 (C), and methanol (D) are shown. The methanogenic pathway is shown in blue, the energy-conserving electron transport chain in red, and biosynthetic pathway in purple. The steps catalyzed by Ech and ferredoxin-dependent enzymes are labeled in green. See text for detailed discussion.
