TABLE 1.
The relative contents of 17 metabolites in the Control, Model, Glutathione, and b1,4-GL groups.
| NO | Metabolites | Control | Model | Glutathione | 1,4-GL | VIP value |
|---|---|---|---|---|---|---|
| 1 | Bile acid | 25.04 ± 9.38 | 28.67 ± 14.16 | 35.17 ± 9.32 | 27.52 ± 4.45 | 0.75 |
| 2 | Lipid | 66.87 ± 15.81 | 57.38 ± 25.17 | 78.25 ± 20.70 | 73.48 ± 26.68 | 0.49 |
| 3 | Leucine | 21.49 ± 7.56 | 21.11 ± 7.79 | 38.44 ± 8.76 a | 37.53 ± 12.66 a | 1.13 |
| 4 | Isoleucine | 12.87 ± 7.86 a | 6.07 ± 2.24 | 17.20 ± 4.51 a | 13.29 ± 3.06 a | 1.23 |
| 5 | Lactate | 1.97 ± 0.54 | 1.93 ± 0.52 | 2.55 ± 0.13 a | 2.29 ± 0.37 | 0.81 |
| 6 | Alanine | 125.38 ± 27.55 | 131.83 ± 31.04 | 132.00 ± 7.26 | 133.82 ± 10.80 | 0.41 |
| 7 | Acetate | 19.18 ± 6.39 | 22.72 ± 6.94 | 34.63 ± 4.66 a | 18.47 ± 3.47 | 1.42 |
| 8 | N-Acetylglucosamine | 132.73 ± 29.94 | 126.85 ± 36.55 | 155.24 ± 22.85 | 173.99 ± 50.09 a | 0.96 |
| 9 | Glutamic acid | 93.36 ± 28.78 | 65.36 ± 29.82 | 107.58 ± 12.35 a | 73.56 ± 10.36 | 0.95 |
| 10 | Glutamine | 39.26 ± 5.60 a | 18.52 ± 5.84 | 34.89 ± 9.08 a | 25.54 ± 6.33 a | 1.17 |
| 11 | Trimethylamine | 23.95 ± 4.63 | 23.35 ± 7.18 | 35.06 ± 3.43 a | 32.15 ± 8.99 a | 1.09 |
| 12 | Choline | 256.82 ± 73.34 | 188.84 ± 89.20 | 350.75 ± 27.78 a | 239.35 ± 20.84 | 1.02 |
| 13 | Lysine | 0.83 ± 0.03 a | 0.58 ± 0.17 | 0.77 ± 0.07 | 0.62 ± 0.17 | 1.07 |
| 14 | Uridine | 18.07 ± 1.82 | 16.63 ± 2.66 | 22.67 ± 5.55 | 17.48 ± 0.83 | 0.97 |
| 15 | Hypoxanthine | 12.16 ± 1.83 | 9.16 ± 4.20 | 13.54 ± 1.60 | 11.59 ± 1.88 | 0.98 |
| 16 | Formate | 12.73 ± 1.50 a | 7.53 ± 2.39 | 12.41 ± 1.53 a | 7.83 ± 1.20 | 1.28 |
| 17 | Nicotinic acid | 11.96 ± 3.37 a | 6.52 ± 1.78 | 12.75 ± 2.06 a | 9.16 ± 0.80 a | 1.02 |
a
indicates statistical significance when compared to the Model group, p < 0.05.