Figure 6.
Representative rod and cone ERG recordings of Rp1+/+ and Rp1−/− mice at ages 2 (2M), 6 (6M) and 12 (12M) months. Serial recordings from rods show responses to flashes of short-wavelength (Wratten 47A; λmax = 470 nm) light increasing in intensity over a 3.0-log unit range (in 0.6-log unit steps), up to the maximum intensity (top traces, 0.668 cd⋅s/m2). Cone-dominated responses were stimulated by a series of white flashes of increasing intensity (in 0.3-log unit steps) on a rod-saturating background (32 cd/m2) up to the maximum intensity (8.46 cd⋅s/m2).