Figure 5.
A structural model for the RXRα/SMRT-ID2 complex. (A) An overview of the RXRα/SMRT-ID2 complex. The SMRT is shown in gold and RXR is in blue except the AF-2 helix in red and helix -11 in yellow. (B) A close view of the RXRα/SMRT-ID2 interface. The key residues of SMRT-ID2 and RXR are noted. (C) A superposition of the RXR AF-2 helix (red) from its tetramer structure with the SMRT corepressor helix (gold) in the RXR coactivator-binding site (shown in a surface representation colored with atom types).