. Author manuscript; available in PMC: 2025 Jul 23.

Published in final edited form as: Am J Physiol Heart Circ Physiol. 2025 Jun 23;329(2):H291–H302. doi: 10.1152/ajpheart.00126.2025

Table 1.

Characteristics of male wild-type littermates and eBACE2^−/− mice.

Parameters	Cdh5-Cre⁻;BACE2^flox/flox (WT littermates)	Cdh5-Cre⁺;BACE2^flox/flox (eBACE2^−/−)	p-value
BW (g)	26.5±0.4 (21)	26.6±0.4 (21)	0.981
Tamoxifen citrate (mg/kg BW/day)	42.3±1.1 (21)	41.9±0.9 (21)	0.777
Glucose (mg/dL)	187±9 (10)	185±8 (10)	0.873
Aβ_1–40 (pg/mL)	230±17 (10)	234±10 (10)	0.849
Total Cholesterol (mg/dL)	45.6±3.7 (10)	49.2±1.3 (10)	0.367
HDL (mg/dL)	32.0±2.7 (10)	34.7±1.0 (10)	0.365
Triglyceride (mg/dL)	74.0±6.9 (10)	91.4±4.5 (10) ^*	0.0496

Data are means ± SEM, and the numbers of mice are indicated in the parentheses. Wild-type littermates and eBACE2^−/− mice were compared by unpaired Student t-test, and p-values (two-tailed) are shown in this table. BW denotes body weight; Aβ, amyloid-β; WT, wild-type; *, statistically significant.