Table 3.
Association of AGT M235T genotype with clinical characteristics in Debre Tabor Referral Hospital, Northwest Ethiopia, 2022
| Variables | Genotypes | |||
|---|---|---|---|---|
|
| ||||
| TT (n=65) | MT (n=49) | MM (N=26) | p-value | |
| Sex (M/F) | 30/28 | 30/15 | 16/21 | 0.3818 |
| Age (yr) | 57.72±12.31 | 59.88±10.69 | 58.13±9.89 | 0.5209 |
| Family history HTN (%) | 49.2 % | 61.2 % | 46.1 % | 0.8916 |
| Family history IHD (%) | 16.9 % | 22.4 % | 11.5 % | 0.7646 |
| BMI (Kg/m2) | 22.6±4.2 | 22.6±4.1 | 23.8±4.5 | 0.5085 |
| SBP (mmHg) | 139.2±17.6 | 124.7±10.8 | 124.6±12.9 | < 0.01* |
| DBP (mmHg) | 87.1±9.7 | 79.3±10.6 | 80.3±7.1 | < 0.01* |
| FBS (mg/dl) | 87.0±19.2 | 89.7±6.3 | 86.8±7.2 | 0.2061 |
| TC (mg/dl) | 171.8±58.7 | 169.7±63.5 | 180.5±76.3 | 0.1066 |
| TG (mg/dl) | 124.2±61.0 | 124.7±55.9 | 138.9±75.0 | 0.3577 |
| LDL-C (mg/dl) | 85.8±33.3 | 84.2±33.2 | 91.6±38.5 | 0.6047 |
| HDL-C (mg/dl) | 47.2±10.3 | 46.8±11.4 | 47.2±10.4 | 0.5045 |
| Creatinine (mg/dl) | 0.83±0.13 | 0.78±0.15 | 0.80±0.13 | 0.3857 |
*
Statistically significant differences at P <0.05.