TABLE 3.
Adjusted a logistic regression and multinomial regression models for the prospective associations between each SDQ subscale at age 10 and asthma at age 15 compared to no asthma at age 15 (as reference).
| Current asthma 15 years (n/N = 231/3584) | Asthma endotypes 15 years | |||||
|---|---|---|---|---|---|---|
| Atopic asthma (n/N = 135/2221) | Non‐atopic asthma (n/N = 30/2221) | |||||
| OR a (95% CI) | p‐Value | RRR a (95% CI) | p‐Value | RRR a (95% CI) | p‐Value | |
| SDQ 10 years emotional problems b | 1.50 (0.93–2.43) | .099 | 1.68 (0.90–3.17) | .106 | 1.83 (0.68–4.90) | .230 |
| SDQ 10 years conduct problems b | 0.87 (0.47–1.61) | .664 | 0.70 (0.31–1.57) | .386 | 0.73 (0.16–3.34) | .689 |
| SDQ 10 years hyperactivity/inattention b | 1.20 (0.68–2.11) | .537 | 0.63 (0.27–1.44) | .269 | 2.38 (0.79–7.16) | .123 |
| SDQ 10 years peer problems b | 1.66 (0.94–2.92) | .083 | 2.00 (1.01–3.97) * | .048 | 1.63 (0.45–5.84) | .456 |
| SDQ 10 years problems in prosocial behavior b | 1.12 (0.56–2.24) | .741 | 141 (0.58–3.44) | .455 | 0.59 (0.08–4.66) | .618 |
Note: Significant associations are highlighted in bold.
Covariates and confounders: sex, age (15 years), study group, recruitment region, parental education level, parental atopy, BMI, early‐life infections, eczema ever, allergic rhinitis ever, total energy intake (kcal/day), total starch (percentage of total daily energy intake, % EI), total sucrose (% EI), fruits & vegetables (% EI), pubertal status (10 years).
Borderline/abnormal versus normal.
Significant interaction term of SDQ with onset of puberty (RRR = 0.08, 95% CI = 0.01–0.78, p = .029).