Table 2.
Clinical and biochemical outcomes after unilateral ADX, shown as M (P25, P75)
| AVS group (N = 66) | CXCR4 group (N = 23) | F | P | ||
|---|---|---|---|---|---|
| Biochemical outcomes | DRC (mIU/L) | 11.78(4.11,29.07) | 15.63(7.83,25.18) | 0.000 | 0.990 |
| PAC (ng/dl) | 7.12(5.00,10.40) | 6.33(4.24,10.10) | 0.547 | 0.461 | |
| ARR [(ng/dl)/(mIU/L)] | 0.52(0.27,1.61) | 0.57(0.16,1.19) | 1.335 | 0.251 | |
| K (mmol/L) | 4.31(4.15,4.61) | 4.33(4.19,4.57) | 0.113 | 0.738 | |
| ΔPAC | 19.36(8.15,34.03) | 16.03(8.4,52.40) | 0.327 | 0.569 | |
| ΔDRC | −9.35(−24.16,−2.27) | −12.08(−23.39,−6.33) | 0.369 | 0.545 | |
| ΔK | −0.69(−1.34,0.26) | −0.89(−2.12,−0.48) | 5.289 | 0.024* | |
| Clinical outcomes | Systolic blood pressure (mmHg) | 120.00(120.00,135.00) | 120.00(120.00,135.00) | 0.038 | 0.847 |
| Diastolic blood pressure (mmHg) | 80.00(80.00,90.00) | 80.00(70.00,85.00) | 0.936 | 0.336 | |
| ΔSystolic blood pressure (mmHg) | 27.50(13.00,42.25) | 23.00 (17.00,35.00) | 0.414 | 0.522 | |
| ΔDiastolic blood pressure (mmHg) | 20.05 (6.5,28.50) | 19.00 (10.00,32.00) | 0.024 | 0.877 | |
| ΔDDDa | 1.00(0.25,1.5) | 1.00(0.40,2.00) | 1.022 | 0.315 |
ARR renin/aldosterone ratio, DDD defined average daily dose of antihypertensive drugs, DRC direct renin concentration, PAC plasma aldosterone concentration
ΔPAC preoperative-postoperative change in PAC, ΔDRC preoperative-postoperative elevation in DRC, ΔARR preoperative- postoperative change in ARR, ΔK preoperative-postoperative change in potassium
*P < 0.05, there was a significant difference
aThe daily maintenance dose of common antihypertensive drugs is defined according to the requirements of (https://www.whocc.no/atc_ddd_index/). The DDD definition of common antihypertensive drugs in our centre is presented in Appendix 2-DDD values of common antihypertensive drugs.