TABLE 3.
Showing result of colistin/streptomycin/MCR‐1 antibody checkerboard assays undertaken in avian Escherichia coli isolates.
| Isolate | In combination (µg/Ml) MIC | As single agents (µg/Ml) MIC | FIC Index | Interpretation | ||||
|---|---|---|---|---|---|---|---|---|
| Col | Strept | Ab | Col | Strept | Ab | |||
| 3 | 0.5 | 16 | ≤1.95 | 4 | 16 | ≤1.95 | 2 | Additive |
| 3 | 0.5 | 16 | ≤1.95 | 4 | 16 | ≤1.95 | 2 | Additive |
| 1 | 8 | ≤1.95 | 8 | ≤1.95 | 2 | Additive | ||
| 2 | 2 | 64 | ≤1.95 | 4 | 64 | ≤1.95 | 2 | Additive |
Note: Highlighted cell‐assay undertaken in presence of human serum complement in duplicate.
Abbreviations: Ab, mcr‐1 antibody; Col, colistin; MIC, minimum inhibitory concentration; FIC Index, fractional inhibitory concentration index; Strept, streptomycin.