Table 2.
Univariable and multivariable Cox regression analysis in SCLC patients with BMs
| Characteristics | Categories | Univariable | Multivariable | ||||
|---|---|---|---|---|---|---|---|
| HR | 95%CI | P-value | HR | 95%CI | P-value | ||
| Gender | Male vs. Female | 1.274 | 0.569–2.853 | 0.556 | |||
| Age (years) | ≥ 60 vs. <60 | 1.383 | 0.701–2.727 | 0.349 | |||
| Number of BMs | ≥ 2 vs. Single | 1.192 | 0.623–2.278 | 0.596 | |||
| Concurrent targeted therapy | Yes vs. No | 0.410 | 0.223–0.755 | 0.004 | 0.486 | 0.256–0.924 | 0.028 |
| Radiation type | WBRT + SIB vs. WBRT | 0.471 | 0.265–0.837 | 0.010 | 0.592 | 0.322–1.085 | 0.090 |
SCLC small cell lung cancer, BMs brain metastases, HR hazard ratio, CI confidence interval, WBRT whole brain radiotherapy, SIB simultaneous integrated boost