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. 2025 Jul 24;25:1210. doi: 10.1186/s12885-025-14593-z

Table 2.

Univariable and multivariable Cox regression analysis in SCLC patients with BMs

Characteristics Categories Univariable Multivariable
HR 95%CI P-value HR 95%CI P-value
Gender Male vs. Female 1.274 0.569–2.853 0.556
Age (years) ≥ 60 vs. <60 1.383 0.701–2.727 0.349
Number of BMs ≥ 2 vs. Single 1.192 0.623–2.278 0.596
Concurrent targeted therapy Yes vs. No 0.410 0.223–0.755 0.004 0.486 0.256–0.924 0.028
Radiation type WBRT + SIB vs. WBRT 0.471 0.265–0.837 0.010 0.592 0.322–1.085 0.090

SCLC small cell lung cancer, BMs brain metastases, HR hazard ratio, CI confidence interval, WBRT whole brain radiotherapy, SIB simultaneous integrated boost