Table 1.
Demographic information by cohort
| Variable | Characteristic | MDD-ANH (N = 4,255) |
Other-MDD (N = 1,454) |
p-value |
|---|---|---|---|---|
| Age (years) | Mean (SD) | 41.0 (15.8) | 37.8 (15.0) | < 0.001 |
| Sex | Female | 3,065 (72.0%) | 1,077 (74.1%) | 0.133 |
| Male | 1,190 (28.0%) | 377 (25.9%) | ||
| Race | Asian | 29 (1.4%) | 8 (1.1%) | 0.468 |
| Black/AA | 159 (7.5%) | 47 (6.2%) | ||
| Caucasian | 1,834 (87.0%) | 664 (87.9%) | ||
| Other (including multiple) | 85 (4.0%) | 36 (4.8%) | ||
| Unknown/Not Reported | 2,148 | 699 | ||
| Ethnicity | Hispanic/Latino | 203 (10.0%) | 82 (11.3%) | 0.319 |
| Non-Hispanic/Latino | 1,822 (90.0%) | 641 (88.7%) | ||
| Unknown/Not Reported | 2,230 | 731 | ||
| Insurance: Commercial | N (%) | 2,014 (47.3%) | 718 (49.4%) | 0.177 |
| Insurance: Medicare | N (%) | 384 (9.0%) | 80 (5.5%) | < 0.001 |
| Insurance: Medicaid | N (%) | 313 (7.4%) | 83 (5.7%) | 0.033 |
| Comorbid Anxiety Disorder | N (%) | 1,915 (45.0%) | 656 (45.1%) | 0.941 |
| Comorbid ADHD | N (%) | 413 (9.7%) | 164 (11.3%) | 0.086 |
| Comorbid Post-Traumatic Stress Disorder | N (%) | 286 (6.7%) | 89 (6.1%) | 0.425 |
| Charlson Comorbidity Index | Mean (SD) | 0.6 (1.3) | 0.5 (1.1) | 0.020 |
| Baseline PHQ-9 score | Mean (SD) | 18.2 (4.2) | 13.5 (2.9) | < 0.001 |
P-values for categorical variables were calculated using a chi-square test, p-values for continuous variables are calculated using the Mann-Whitney U test