Fig. 3.

MPA reactivation rates correlate with β-GUSgene variants linked with Faecalibacterium prausnitzii. Correlations between MPA reactivation rates and read mapping rates to beta-glucuronidase (β-GUS) gene variants filtered to represent only those variants observed in at least 50% of kidney transplant recipients (a) and healthy individuals (b), as well as mean normalized abundances of those genes with error bars representing ± 1 s.e. (c, d). Green and beige bars represent β-GUS genes linked with Faecalibacterium prausnitzii in a/c and b/d, respectively. See Supplementary Fig. S7 for a more detailed label with the specific gene markers and Supplementary Fig. S8a and b for correlations between MPA reactivation rates and all observed β-GUS gene variants. *p < 0.05; **p < 0.01; ***p < 0.001. RPKM, reads per kilobase of target sequence per million reads in library