Table 3.
Univariate and multivariate analyses of CSS in the whole population cohort after PSM
| Variables | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
| HR (95%CI) | p-value | HR (95%CI) | p-value | ||
| Age(years) | < 0.0001 | ||||
| < 50 | Reference | Reference | |||
| 50–59 | 1.240(0.964,1.595) | 1.220(0.947,1.571) | 0.124 | ||
| 60–69 | 1.530(1.199,1.952) | 1.397(1.088,1.794) | 0.009 | ||
| 70–79 | 2.468(1.903,3.201) | 2.200(1.677,2.887) | < 0.0001 | ||
| ≥ 80 | 4.465(3.231,6.170) | 3.899(2.780,5.468) | < 0.0001 | ||
| Sex | 0.054 | ||||
| Male | Reference | - | |||
| Female | 1.178(0.998,1.390) | - | - | ||
| Race | 0.540 | ||||
| White | Reference | - | |||
| Black | 1.224(0.812,1.844) | - | - | ||
| Other | 0.930(0.710,1.219) | - | - | ||
| Marital | < 0.0001 | ||||
| Single | Reference | Reference | |||
| Married | 0.891(0.711,1.116) | 0.794(0.631,0.999) | 0.049 | ||
| Other | 1.423(1.100,1.842) | 0.970(0.739,1.273) | 0.827 | ||
| Grade | < 0.001 | ||||
| I | Reference | Reference | |||
| II | 1.116(0.881,1.413) | 1.127(0.888,1.429) | 0.326 | ||
| III/IV | 1.678(1.278,2.203) | 1.704(1.296,2.241) | < 0.001 | ||
| T stage | 0.470 | ||||
| T1 | Reference | - | |||
| T2 | 1.063(0.900,1.256) | - | - | ||
| Tumor Size | 1.014(1.004,1.023) | 0.004 | 1.018(1.008,1.027) | < 0.001 | |
| LN removed | < 0.0001 | ||||
| None | Reference | Reference | |||
| Yes | 0.548(0.464,0.647) | 0.589(0.496,0.700) | < 0.0001 | ||
| Radiation | < 0.0001 | ||||
| None/Unknown | Reference | Reference | |||
| PORT | 1.736(1.463,2.061) | 1.676(1.411,1.989) | < 0.0001 | ||
Note: LN: Lymph nodes; PORT: Postoperative Radiotherapy