2. Yield and Epimer Ratios for the Synthesis of Stable Isotope-Labeled Priority EAs .
| ergot alkaloid- 13 CD 3 | ergometrine & ergometrinine | ergotamine & ergotaminine | ergosine & ergosinine | ergocornine & ergocorninine | ergocryptine & ergocryptinine | ergocristine & ergocristinine |
|---|---|---|---|---|---|---|
| yield [%] | - | 14.9 | - | 19.6 | 29.5 | 8.1 |
| epimer ratio [R%:S%] | 69:31 | 51:49 | 53:47 | 58:42 | 51:49 | 45:55 |
a
Due to the low amount of starting material for ergometrine and ergosine, no yield could be determined for 13CD3-ergometrine/-inine and 13CD3-ergosine/-inine.