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Molecular components that support stores-operated Ca2+ entry (SOCE)
| IP3R1, IP3R2, IP3R3 | inositol trisphosphate receptors, release ER Ca2+ |
| RYR1, RyR2, RyR3 | ryanodine receptors, also release ER Ca2+ |
| STIM1, STIM2 | high, and low, affinity sensors of [Ca2+]ER; activate stores-operated channels (SOCs) |
| Orai1, Orai2, Orai3 | Ca2+-release activated Ca2+ (CRAC) channels, a class of SOCs |
| TRPC1, other TRPCs can function as STIMI -activated SOCs | |
