TABLE 5 -.

Annual burden of PHPT

Strategy	N	Annual cost
PTX	9,133	€ 52,185,962.00*
Active surveillance	1,373	€ 1,486,107.70
Pharmacologic treatments	1,494	€ 2,750,902.00
Total	12,000	€ 56,422,971.70

* By applying the costs established by the NHS and accounting for the additional cost estimated for the first year for all complementary services, the cost of PTX amounts to € 5,714,00. This is calculated by subtracting the € 2,356 net cost of the procedure (as determined in Table 2) from the € 4,588.00 total cost for the first year and then adding the € 3,482 NHS reimbursement.