NOX2	NADPH oxidase 2
CGD	Chronic granulomatous disease
ROS	Reactive oxygen species
NOX	NADPH oxidase
PRR	Proline-rich region
O2•−	Superoxide radical
H2O2	Hydrogen peroxide
OH•	Hydroxyl radical
HOCl	Hypochlorous acid
NCF1	Neutrophil cytosolic factor 1
PX	Phox homology domain
SH3	Src homology domain 3
PKC	Protein kinase C
NMR	Nuclear magnetic resonance
Cryo-EM	Cryo-electron microscopy
PTM	Post-translational modification
UPS	Ubiquitin proteasome system
PAMP	Pathogen-associated molecular pattern
DAMP	Damage-associated molecular pattern
AIR	Autoinhibitory region
FRET	Fluorescence resonance energy transfer
BRET	Bioluminescence resonance energy transfer
PPI	Protein–protein interaction
TNF-α	Tumor necrosis factor alpha
PKA	Protein kinase A
CK2	Casein kinase 2
RA	Rheumatoid arthritis
AD	Alzheimer’s disease
PD	Parkinson’s disease
IBD	Inflammatory bowel disease
VEGF	Vascular endothelial growth factor
MMP	Matrix metalloproteinases
TGF-β	Transforming growth factor beta
NF-κB	Nuclear factor kappa B
NAFLD	Non-alcoholic fatty liver disease
PRR	Pattern recognition receptor
SAR	Structure–activity relationship
IP6	Inositol hexaphosphate
WAVE	Wiskott–Aldrich syndrome protein family verprolin homologous protein
PROTAC	Proteolysis targeting chimera