Table 4.

Histological measurements of bone-to-implant contact (BIC) evaluated at different levels of the implants and as total amount.

		Total	Apical	Middle	Coronal
Two weeks	Control	16.1 ± 8.2 ‡	5.5 ± 3.4 ‡	18.2 ± 15.4 ‡	24.4 ± 16.5 ‡
	Test (Regenfast®)	17.9 ± 8.8 ‡	4.0 ± 4.5 ‡	15.0 ± 18.2 ‡	34.7 ± 7.6
	p-value	0.350	0.544	0.602	0.064
Ten weeks	Control	42.3 ± 7.8 ‡	29.0 ± 16.0 ‡	41.3 ± 10.8 ‡	56.7 ± 11.2 ‡
	Test (Regenfast®)	40.2 ± 9.8 ‡	27.2 ± 12.8 ‡	48.0 ± 19.1 ‡	45.4 ± 23.9
	p-value	0.687	0.833	0.352	0.295

p < 0.05 between test and control (paired t-test or Wilcoxon matched-pairs signed-rank test). ^‡, p < 0.05 between periods (unpaired t-test or Mann–Whitney test).