Table 2.
Case report 1. The table shows the anthropometric parameters, the lower limb symptom score measured with a questionnaire, the pain score evoked by the adipose tissue fold and the adipose tissue thickness measured with the ultrasound of case report 1. The data before (T0) and after 3 months of therapy (T3) and the changes (Delta T3–T0) are reported. The patient was treated with exenatide LAR 2 mg/week for 3 months in association with moderate physical activity (2 h/week). The patient did not change her diet. RPS: Ricolfi–Patton Score.
| Parameters | T0 | T3 | Delta (T3–T0) |
|---|---|---|---|
| Body weight (kg) | 89 | 89 | 0 |
| Waist circumference (cm) | 101 | 98 | −3 |
| Hip circumference (cm) | 126 | 125 | −1 |
| Symptoms 1 | |||
| Spontaneous pain in the lower limbs | 3 | 3 | 0 |
| Feeling of swelling in the lower limbs | 3 | 3 | 0 |
| Pressure pain in the lower limbs | 4 | 2 | −2 |
| Ease of bruising | 3 | 1 | −2 |
| Total symptom score | 52 | 36 | −16 |
| Evoked pain or lipoalgia 2 | |||
| Lower medial third of the leg | 4 | 3 | −1 |
| Posterior middle third of the leg | 3 | 3 | 0 |
| Medial upper third of the leg | 4 | 2 | −2 |
| Medial lower third of the thigh | 4 | 4 | 0 |
| Medial upper third of the thigh | 4 | 4 | 0 |
| Lateral upper third of the thigh | 4 | 3 | −1 |
| Lateral lower third of the thigh | 4 | 3 | −1 |
| Lower abdomen | 3 | 1 | −2 |
| Lateral subscapular region | 3 | 1 | −2 |
| Arm | 2 | 3 | +1 |
| Forearm | 0 | 0 | 0 |
| Lower body pain score | 30 | 23 | −7 |
| Upper body pain score | 5 | 4 | −1 |
| Total body pain score or RPS | 36 | 27 | −9 |
| Thickness of subcutaneous tissue 3 | |||
| Lower medial third of the leg (mm) | 18.4 | 13.3 | −5.1 |
| Medial upper third of the leg (mm) | 9.6 | 7.21 | −2.39 |
| Medial lower third of the thigh (mm) | 33.3 | 27.6 | −5.7 |
| Medial upper third of the thigh (mm) | 36.3 | 28.6 | −7.7 |
| Upper anterior third of the thigh (mm) | 13.8 | 11.2 | −2.6 |
| Anterior middle third of the thigh (mm) | 24.5 | 22.0 | −2.5 |
| Lateral lower third of the thigh (mm) | 29.1 | 26.5 | −2.6 |
| Upper lateral third of the leg (mm) | 11.4 | 8.03 | −3.37 |
| Lower lateral third of the leg (mm) | 11.4 | 8.70 | −2.7 |
| Lower abdomen (mm) | 35.3 | 27.3 | −8 |
| Upper abdomen (mm) | 35.3 | 29.0 | −6.3 |
| Midpoint upper arm (mm) | 12.4 | 15.7 | +3.3 |
| Midpoint forearm (mm) | 6.21 | 5.8 | −0.41 |
1 Symptoms are reported on a 6-point Likert scale (0 = none, 1 = very mild, 2 = mild, 3 = moderate, 4 = severe and 5 = very severe). The total symptom score is the sum of the individual scores for the 17 symptom items of the questionnaire (ranging from 0 to 85). 2 Pain evoked, or lipoalgia, was scored on a numeric rating scale from 0 to 4 (0 = no pain, 1 = mild pain, 2 = moderate pain, 3 = severe pain and 4 = very severe pain). The lower body pain score is the sum of the lower limb and abdomen scores (ranging from 0 to 32). The upper body pain score is the sum of the scores for the upper limbs and back (ranging from 0 to 12). The total body pain score or Ricolfi–Patton Score (RPS) is the sum of the value of all points (ranging from 0 to 44). 3 The thickness of the subcutaneous tissue was measured by ultrasound and includes all the tissue, from the skin to the muscular fascia.