| TRD | Treatment-resistant depression |
| MDD | Major depressive disorder |
| SSRIs | Selective serotonin reuptake inhibitors |
| SNRIs | Serotonin–norepinephrine reuptake inhibitors |
| MAOIs | Monoamine oxidase inhibitors |
| TCAs | Tricyclic antidepressants |
| IV | Intravenous |
| IM | Intramuscular |
| NMDA | N-methyl-D-aspartate |
| AMPA | α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid |
| BDNF | Brain-derived neurotrophic factor |
| mTOR | Rapamycin |
| CBT | Cognitive Behavioral Therapy |
| HPA | Hypothalamic–pituitary–adrenal |
| IL-6 | Interleukin-6 (IL-6) |
| TNF-α | Tumor necrosis factor-alpha |
| PTSD | Post-traumatic stress disorder |
| KAP | Ketamine-assisted psychotherapy |
| KIC | Ketamine-induced cystitis |
| GAG | Glycosaminoglycan |
| ANCOVA | Analysis of covariance |