Table 2.
Studies using biopolymers to bioengineer human liver from LSCs are summarised below and detailed in Supplementary Table S2.
| Biopolymer/Substrate | Maintenance | Differentiation |
|---|---|---|
| Matrigel | 90 | 96 |
| Matrigel (GFR) | 28 | 23 |
| Collagen-I | 14 | 11 |
| Fibronectin | 1 | - |
| Gelatine | 1 | 1 |
| Gelatine-Alginate | - | 1 |
| GelMA | - | 1 |
| Hyaluronic Acid | 1 | 1 |
| HydroxTM | - | 1 |
| Liver ECM | - | 1 |
| Laminin 332 | - | 1 |
| Laminin 511-PIC 1 | - | 1 |
| PIC-LEC 2 | - | 1 |
| PEG | - | 1 |
| PCL | - | 1 |
| Suspension Culture | 3 | 10 |
| No coating | 21 | 15 |
1 PIC = polyisocyanopeptides, 2 PIC-LEC = PIC-laminin 111-entactin complex.