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. 2025 Jul 18;14(14):5100. doi: 10.3390/jcm14145100
NLR neutrophil to lymphocyte ratio
IPF idiopathic pulmonary fibrosis
ILDs interstitial lung diseases
f-ILD fibrotic interstitial lung disease
UIP usual interstitial pneumonia
AE-IPF acute exacerbation of idiopathic pulmonary fibrosis
MiRNA microRNA
EMT epithelial-myofibroblasts’ transition
TGF-β transforming growth factor-beta
AECIIs Type-II alveolar epithelial cells
ILCs immune lymphoid cells
ECM extracellular matrix
NE neutrophil elastase
NET neutrophil extracellular trap
IL-4 interlukin-4
IL-10 interleukin-10
IL-13 Interleukin-13
IFN-gamma Interferon-gamma
CCL3 chemokine C-C motif ligand 3
CCL4 chemokine C-C motif ligand 4
AMs alveolar macrophages
M1 classically activated macrophages
M2 alternatively activated macrophages
IL-5 interleukin-5
IL-9 interleukin-9
AECIs type-I alveolar epithelial cells
WBCs white blood cells
MMPs metalloproteinases
MMP-9 metalloproteinase-9
MMP-7 matrix metalloproteinases-7
AECs alveolar epithelial cells
MMP-8 metalloproteinase-8
BALF bronchoalveolar lavage fluid
MPO myeloperoxidase
Th1 T helper 1
Th2 T helper 2
T regs regulatory T cells
FVC forced vital capacity
DLco diffuse capacity for carbon monoxide
RCTs randomized controlled trials
%pp percent predicted
GSDMD Gasdermin D
SP-D Surfactant protein D
OPN Osteopontin
GAP index Gender-age-physiology index
ICAM-1 intercellular adhesion molecule-1
KL-6 Krebs von Den Lungen-6
CCL18 C-C motif ligand-18
COPD Chronic obstructive pulmonary diseases