17β-HSD	17β-Hydroxysteroid Dehydrogenase
AChE	Acetylcholinesterase
AD	Alzheimer’s disease
ADME	Absorption, Distribution, Metabolism, and Excretion
AF-1/AF-2	Activation Function-1/Activation Function-2
AFP	Alpha-fetoprotein
Akt	Protein Kinase B
ALP	Alkaline phosphatase
ALT	Alanine transaminase
AMPK	AMP-Activated Protein Kinase
Ang II	Angiotensin II
ANS	8-anilino-1-naphthalenesulfonic acid
APP	Amyloid-β precursor protein
AREG	Amphiregulin
AST	Aspartate transaminase
AT1R	Angiotensin II Type 1 Receptor
BAD	Bcl-2-associated agonist of cell death
BDNF	Brain-Derived Neurotrophic Factor
CAT	Catalase
CCl4	Carbon Tetrachloride
CD	Circular dichroism
CIRI	Cerebral ischemia/reperfusion injury
CNS	Central nervous system
CREB	cAMP Response Element-Binding Protein
CRP	c-reactive protein
CUMS	Chronic unpredictable mild stress
CXCL-12	C-X-C Motif Chemokine Ligand 12
CXCL1	CXC Motif Chemokine Ligand 1
CYP3A4	Cytochrome P450 3A4
DBD	DNA-Binding Domain
DENA	Diethylnitrosamine
DMBA	7,12-Dimethylbenz[a]anthracene
DMS	Dimethylhydrazine dihydrochloride
DRIA	Daidzein-rich isoflavones aglycone
DSS	Dextran sodium sulfate
EGFR	Epidermal Growth Factor Receptor
EGR-1	Early Growth Response Protein 1
ER	Estrogen Receptor
ERK	Extracellular signal-regulated kinase
ERα	Estrogen Receptor Alpha
ERβ	Estrogen Receptor Beta
FAAH	Fatty acid amide hydrolase
FoxM1	Forkhead Box M1
GLUT1/GLUT4	Glucose Transporter 1/4
GnRH	Gonadotropin-Releasing Hormone
GPC3	Glypican-3
GPER	G-protein-coupled Estrogen Receptor
GPER	G protein-coupled estrogen receptor
GSH	Glutathione
GSK3	Glycogen synthase kinase 3
GSK3αβ	Glycogen Synthase Kinase 3 alpha/beta
GSSG	Glutathione disulfide
GST	Glutathione S-transferases
H2O2	Hydrogen Peroxide
HCC	Hepatocellular carcinoma
HMGB1	High mobility group box 1
HRT	Hormone Replacement Therapy
I/R	Ischemia/reperfusion
IC50	Half-maximal inhibitory concentration
IG	Intragastrically
IGD	Isoflavone Genistein and Daidzein combination
IL	Interleukin
IP	Intraperitoneally
LBD	Ligand-Binding Domain
LFPI	Lateral fluid percussion injury
LPO	lipid peroxidation
MAPK	Mitogen-Activated Protein Kinase
MAPK/ERK	Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase
MCAO	Middle cerebral artery occlusion
MKRN3	Makorin Ring Finger Protein 3
MMP-9	Matrix Metalloproteinase 9
MnSOD	Manganese Superoxide Dismutase
MPO	Myeloperoxidase
mTOR	Mechanistic Target of Rapamycin
NLRP3	Nod-like receptor protein 3
NO	Nitric oxide
NSCLC	Non-small cell lung cancer
OGD/R	Oxygen-glucose deprivation/reoxygenation
OPG	Osteoprotegerin
OVX	Ovariectomy or Oophorectomy
PDB	Protein Data Bank
PGC-1α	Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-Alpha
PGC-1α	Peroxisome proliferator-activated receptor-gamma coactivator 1α
PGE2	Prostaglandin E2
PI3K	Phosphatidylinositol 3-Kinase
PKCγ	Protein Kinase C Gamma
PO	Per oral
PPAR-γ	Peroxisome proliferator-activated receptor-γ
PTZ	Pentylenetetrazole
RANKL	Receptor activator of nuclear factor κB ligand
RAS	Renin–Angiotensin System
RCT	Randomized Controlled Trial
ROS	Reactive Oxygen Species
Runx-2	Runt-related transcription factor 2
SC	Subcutaneously
SERM	Selective Estrogen Receptor Modulator
SIRT1	Sirtuin 1
SOD	Superoxide dismutase
SRC3	Steroid Receptor Coactivator 3
STAT3	Signal Transducer and Activator of Transcription 3
SULTs	Sulfotransferases
T2DM	Type 2 diabetes mellitus
TACE	Tumor necrosis factor-α converting enzyme
TBARS	Thiobarbituric Acid Reactive Substances
TBI	Traumatic brain injury
TEM	Transmission electron microscopy
TGF-β1	Transforming Growth Factor Beta 1
TOP	Topical administration
Trpv6	Transient Receptor Potential Vanilloid 6
TXA2	Thromboxane A2
UGTs	UDP-Glucuronosyltransferases
VEGF	Vascular endothelial growth factor
VMS	Vasomotor Symptoms
YES assay	Yeast Estrogen Screen Assay