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. 2025 Jul 21;26(14):6992. doi: 10.3390/ijms26146992
4EBP1 4E-binding protein 1
5-HT Serotonin
AD Alzheimer’s disease
ASD Autism spectrum disorder
BBB Blood–brain barrier
BCAAs Branched-chain amino acids
BCAT Branched-chain amino acid aminotransferase
BCKAs Branched-chain α-keto acids
BCKDH Branched-chain α-keto acid dehydrogenase complex
BCKDK Branched-chain ketoacid dehydrogenase kinase
BMI Body mass index
CNS Central nervous system
CSF Cerebrospinal fluid
DA Dopamine
DALYs Disability-adjusted life years
EMT Epithelial–mesenchymal transition
FMT Fecal microbiota transplantation
GABA Gamma-aminobutyric acid
GBA Gut–brain axis
GC-MS Gas chromatography mass spectrometry
GI Gastrointestinal
GWAS Genome-wide association studies
HPLC-FLD High-performance liquid chromatography
ILE Isoleucine
KIC α-ketoisocaproate
KIV α-ketoisovalerate
KMV α-keto-β-methylvalerate
L-dopa Levodopa
LAT1 L-type amino acid transporter 1
LC-MS Liquid chromatography-mass spectrometry
LEU Leucine
LID Levodopa-induced dyskinesia
LPS Lipopolysaccharide
MCI Mild cognitive impairment
MPTP 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
MSA Multiple system atrophy
MSUD Maple Syrup Urine Disease
NMDA N-methyl-D-aspartate
PD Parkinson’s disease
PPM1K Protein phosphatase, Mg2+/Mn2+ dependent 1K
PSP Progressive supranuclear palsy
RBD REM sleep behavior disorder
REM Rapid eye movement
ROS Reactive oxygen species
S6K S6 kinase
SCFAs Short-chain fatty acids
SNP Single-nucleotide polymorphism
T2DM Type 2 diabetes mellitus
TCA Tricarboxylic acid
TRP Tryptophan
TYR Tyrosine
VAL Valine
mTORC1 Mechanistic target of rapamycin complex 1