Table 2.

Lung organoids derived from different cell sources

Cell Sources		Types of Lung Organoids	References
PSCs	induced PSCs	airway and alveolar structures	[53]
		alveolar organoids	[54]
		alveolar organoids	[55]
		airway organoids	[56]
		airway and alveolar organoids	[57]
	embryonic stem cells	airway spheroids	[58]
		lung organoids	[59]
patient-derived samples	tumor tissue of primary lung cancer patients and patient-derived xenograft	NSCLC organoids	[60]
	patient-derived tissues	LADC organoids	[61]
	fragments tumor tissues	LCOs	[62]
	nasal brushing samples of PCD patients	COPD bronchial organoids	[63]
	MSE samples	LCOs	[64]
normal samples	bronchial epithelial cells, fibroblasts, and microvascular endothelial cells	airway organoids	[65]
	primary lung tissues	alveolar organoids	[66]
		airway and alveolar organoids	[67]

PSCs: pluripotent stem cells; NSCLC: non-small cell lung cancer; LADC: lung adenocarcinoma; LCOs: lung cancer organoids; PCD: primary ciliary dyskinesia; COPD: chronic obstructive pulmonary disease; MSE: malignant serous effusion