ACh	acetylcholine
AChE	acetylcholinesterase
AD	Alzheimer’s disease
ApoE	apolipoproteinE
APP	amyloid precursor protein
AR	autoradiography
ATP	adenosine triphosphate
Aβ	beta amyloid
α-BTX	alpha-bungarotoxin
BACE1	beta-site amyloid precursor protein cleaving enzyme 1
BFCS	basal forebrain cholinergic system
CA1	cornu ammonis 1
CA3	cornu ammonis 3
CaMKII	Ca2+/calmodulin-dependent protein kinase II
CAP	cholinergic anti-inflammatory pathway
CD	cluster of differentiation
E-LTP	early long-term potentiation
eNMDAR	extrasynaptic NMDA receptor
EphB2	ephrin type-B receptor 2
ERK	extracellular signal-regulated kinase
GABA	gamma-aminobutyric acid
GCLC	glutamate-cysteine ligase catalytic subunit
GLAST	glutamate aspartate transporter
GSK	glycogen synthase kinase
HO1	heme oxygenase I
IHC	immunohistochemistry
IkBa	NF-κB inhibitor alpha
IL	interleukin
IP3	inositol triphosphate
ISH	in situ hybridization
JAK2	Janus kinase 2
L-LTP	late-long-term potentiation
LPS	lipopolysaccharide
LTD	long-term depression
LTP	long-term potentiation
mAChR	muscarinic acetylcholine receptor
MAPK	mitogen-activated protein kinase
MCI	mild cognitive impairment
mEPSC	miniature excitatory postsynaptic current
MIP-1α	macrophage inflammatory protein-1 alpha
MLA	methyllycaconitine
MPP+	1-methyl-4-phenylpyridinium
nAChR	nicotinic acetylcholine receptor
NADPH	nicotinamide adenine dinucleotide phosphate
NF-kB	nuclear factor-kappa B
NGF	nerve growth factor
NgR1	nogo receptor 1
NMDA	N-methyl-D-aspartate
Nrf-2	nuclear factor erythroid 2–related factor 2
P2X7R	purinergic P2X7 receptor
p75NTR	p75 neurotrophin receptor
PAMP	pathogen-associated molecular pattern
PET	positron emission tomography
PI3K	phosphoinositide 3-kinase
PKA	protein kinase A
PKC	protein kinase C
PLC	phospholipase C
PP2B	Serine/threonine protein phosphatase 2B (calcineurin)
Prpc	cellular prion protein
PS1	presenilin 1
RAGE	receptor for advanced glycation end products
RANTES	regulated on activation, normal T cell expressed and secreted
ROS	reactive oxygen species
shRNA	short hairpin RNA
STAT3	signal transducer and activator of transcription 3
STEP	Striatal-enriched phosphatase
TNF	tumor necrosis factor
TR-FRET	time-resolved fluorescence energy transfer
TXNRD1	thioredoxin reductase 1
VGCC	voltage-gated Ca2+ channel
WB	Western blot