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. 2025 Jul 21;23(7):293. doi: 10.3390/md23070293

Table 3.

Bioactive peptides derived from tuna.

Source Extraction Site Active Substance Name Activity Reference
Yellowfin tuna Dark muscles KPLSeCPK α-glucosidase inhibition [76]
Skipjack tuna Flesh of fish FQLSAER, GEVDDSIQE, YEAFVK, KSIDDVEE Umami peptide [77]
Bluefin
tuna
Skin GPSGGGYDV DPP-IV inhibitory peptide [78]
Bluefin
tuna
Skeletal myosin LADW, MEIDD, VAEQE, EEAEGT Umami peptide [79]
Yellowfin tuna Trimmings HIAEEADRK
AEQAESDKK
Immunomodulatory peptide [80]
Skipjack tuna Muscles ACECD XODI peptide [81]
Skipjack tuna Skin SJGAP Antimicrobial peptide [82]
Bluefin
tuna
Skeletal myosin EEAGGATAAQIEM Antiviral peptide [83]
Yellowfin tuna Pancreas LLDF Ache inhibitory peptide [84]
Skipjack tuna Dark muscles APP, PPP, DPLL, EAVP, EAIP DPP-IV inhibitory peptide [85]