Table 6.
The effect of compounds 19a and 22b on the distribution of the apoptotic cells in A549 cells.
| Compound/Cell Line | Apoptosis | Necrosis | ||
|---|---|---|---|---|
| Total | Early | Late | ||
| Cont. A549 | 2.38 ± 0.31 | 0.48 ± 0.10 | 0.17 ± 0.02 | 1.72 ± 0.23 |
| 19a/A549 | 37.70 ± 1.40 **** | 9.72 ± 1.06 *** | 23.13 ± 0.73 **** | 4.84 ± 0.34 |
| 22b/A549 | 27.48 ± 0.57 **** | 5.92 ± 0.74 *** | 18.21 ± 0.12 **** | 3.35 ± 0.49 |
Data is represented as the mean ± SD of three independent experiments. (Significance determined by unpaired sample t-test where and *** indicates p < 0.001, **** indicates p < 0.0001 levels of significance).