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. 2025 Jul 11;13:e68143. doi: 10.2196/68143

Table 4.

Descriptive statistics of people living with HIV, preexposure prophylaxis (PrEP) users, postexposure prophylaxis (PEP) users, and people not living with HIV cohorts.

Characteristics People living with HIV (n=132,664; confidence level 1-2) People living with HIV (n=152,282; confidence level 1-3) PrEP users (n=36,088) PEP users (n=4120)a People not living with HIV (n=20,639,675)
Race or ethnicity, n (%)

Hispanic or Latinx, any race 20,925 (15.8) 23,346 (15.3) 5829 (16.2) 403 (9.8) 2,628,308 (12.7)

Non-Hispanic American Indian or Alaska Native 615 (0.5) 684 (0.4) 163 (0.5) <20 (0.5) 85,524 (0.4)

Non-Hispanic Asian 2753 (2.1) 3517 (2.3) 1726 (4.8) 222 (5.4) 729,491 (3.5)

Non-Hispanic Black or African American 49,769 (37.5) 55,144 (36.2) 4534 (12.6) 784 (19) 2,909,443 (14.1)

Non-Hispanic combinedb 903 (0.7) 1150 (0.8) 505 (1.4) 40 (1) 281,450 (1.4)

Non-Hispanic Native Hawaiian or Pacific Islander 247 (0.2) 300 (0.2) 88 (0.2) <20 (0.5) 67,808 (0.3)

Non-Hispanic White 48,604 (36.6) 57,479 (37.7) 19,663 (54.5) 2119 (51.4) 11,966,553 (58)

Unknown 8848 (6.7) 10,662 (7) 3580 (9.9) 512 (12.4) 1,971,098 (9.6)
Age (y), median (IQR) 51 (38-61) 51 (37-61) 36 (30-46) 35 (28-44) 44 (26-63)
Sex, n (%)

Female 42,093 (31.7) 49,846 (32.7) 4253 (11.8) 2693 (65.4) 11,579,223 (56.1)

Male 90,496 (68.2) 102,332 (67.2) 31,722 (87.9) 1399 (34) 9,044,853 (43.8)

Combined or unknownc 75 (0.1) 104 (0.1) 113 (0.3) <20 (0.5) 15,599 (0.1)
Comorbidity, n (%)

Myocardial infarction 9265 (7) 10,349 (6.8) 482 (1.3) 57 (1.4) 795,829 (3.9)

Congestive heart failure 10,926 (8.2) 12,106 (7.9) 406 (1.1) 42 (1) 998,313 (4.8)

Peripheral vascular disease 8002 (6) 8971 (5.9) 352 (1) 52 (1.3) 787,932 (3.8)

Cerebrovascular disease 9082 (6.8) 10,123 (6.6) 492 (1.4) 76 (1.9) 977,070 (4.7)

Dementia 3177 (2.4) 3638 (2.4) 225 (0.6) 63 (1.5) 475,742 (2.3)

Chronic lung disease 40,080 (30.2) 44,328 (29.1) 5617 (15.6) 716 (17.5) 3,562,138 (17.3)

Rheumatologic disease 10,245 (7.7) 11,502 (7.6) 1280 (3.5) 139 (3.4) 1,097,753 (5.3)

Peptic ulcer 4445 (3.4) 4919 (3.2) 466 (1.3) 61 (1.5) 335,672 (1.6)

Liver disease 32,690 (24.6) 35,536 (23.3) 2965 (8.2) 320 (7.8) 1,314,849 (6.4)

Diabetes 28,307 (21.3) 31,731 (20.8) 2631 (7.3) 321 (7.8) 2,750,693 (13.3)

Hemiplegia or paraplegia 3751 (2.8) 4124 (2.7) 121 (0.3) 32 (0.8) 281,201 (1.4)

Kidney disease 26,015 (19.6) 28,288 (18.6) 1142 (3.2) 157 (3.8) 1,681,615 (8.1)

Cancer 20,035 (15.1) 22,447 (14.7) 1399 (3.9) 143 (3.5) 1,866,452 (9)

Hypertension 63,025 (47.5) 69,487 (45.6) 7464 (20.7) 691 (16.9) 5,904,993 (28.6)

Tobacco smoking 34,189 (25.8) 37,120 (24.4) 5830 (16.2) 550 (13.4) 1,844,538 (8.9)
BMI, n (%)

Underweight 2280 (1.7) 2931 (1.9) 378 (1) 90 (2.2) 1,156,445 (5.6)

Healthy weight 20,789 (15.7) 23,743 (15.6) 6684 (18.5) 710 (17.3) 2,837,262 (13.7)

Overweight 35,471 (26.7) 39,718 (26.1) 10,600 (29.4) 864 (21.1) 3,565,102 (17.3)

Obese 52,872 (39.9) 59,238 (38.9) 12,240 (33.9) 1369 (33.4) 6,260,259 (30.3)

Missing 21,252 (16) 26,652 (17.5) 6186 (17.1) 1066 (26) 6,820,607 (33)

aThe PEP cohort is estimated to obfuscate any groups with counts <20 to follow National Clinical Cohort Collaborative governance rules. This will also cause percentages not to sum to 100 in this group.

bIncludes individuals with race and ethnicity variable values that do not include Hispanic, White, Black or African American, Asian, American Indian or Alaska Native, and Native Hawaiian or Other Pacific Islander.

cIncludes individuals with sex variable values that do not include male or female.