Table 2.
Univariate analysis of risk factors associated with 28-day mortality.
| Variable | HR (95% CI) | p value |
|---|---|---|
| Demographics | ||
| Gender, male | 0.73 (0.33, 1.60) | 0.428 |
| Age, years | 1.05 (1.01, 1.09) | 0.008 |
| Comorbidities | ||
| Diabetes | 1.65 (0.74, 3.67) | 0.223 |
| Immunosuppression | NA* | 0.998 |
| Hypertension | 1.53 (0.69, 3.37) | 0.293 |
| COPD | NA* | 0.997 |
| CKD | 1.49 (0.45, 4.99) | 0.516 |
| Cardiac parameters | ||
| LVID, cm | 1.07 (0.95, 1.21) | 0.286 |
| TAPSE, cm | 0.01 (0.00, 0.04) | <0.001 |
| LVEF-S, % | 0.83 (0.79, 0.88) | <0.001 |
| Laboratory values | ||
| NT-proBNP, pg./mL† | 1.00 (1.00, 1.0001) | 0.130 |
| cTnI, ng/mL | 1.58 (1.25, 1.99) | <0.001 |
| APACHE II score | 1.24 (1.16, 1.34) | <0.001 |
| SOFA score | 0.89 (0.67, 1.19) | 0.434 |
| Lactate, mmol/L | 1.22 (1.02, 1.46) | 0.026 |
| PCT, ng/mL | 1.008 (0.998, 1.019) | 0.110 |
| LDH, IU/L | 1.000 (1.000, 1.000) | 0.749 |
| AG, mmol/L | 1.04 (0.99, 1.11) | 0.127 |
| CK, IU/L | 1.000 (1.000, 1.000) | 0.747 |
* NA indicates hazard ratio could not be calculated due to zero events in one group. † HR presented to 4 decimal places due to small effect size. COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease; LVID, left ventricular internal diameter; TAPSE, tricuspid annular plane systolic excursion; LVEF-S, left ventricular ejection fraction-Simpson; NT-proBNP, N-terminal pro-brain natriuretic peptide; cTnI, cardiac troponin I; PCT, procalcitonin; LDH, lactate dehydrogenase; AG, anion gap; CK, creatine kinase; APACHE, Acute Physiology and Chronic Health Evaluation; SOFA, Sequential Organ Failure Assessment.