Skip to main content
CMAJ : Canadian Medical Association Journal logoLink to CMAJ : Canadian Medical Association Journal
. 1999 Mar 23;160(6):805–811.

Direct costs of coronary artery bypass grafting in patients aged 65 years or more and those under age 65

G Naglie 1, C Tansey 1, M D Krahn 1, K O'Rourke 1, A S Detsky 1, H Bolley 1
PMCID: PMC1230159  PMID: 10189424

Abstract

BACKGROUND: Over the past 20 years, there have been marked increases in rates of coronary artery bypass grafting (CABG) among older people in Canada. The objectives of this study were to accurately estimate the direct medical costs of CABG in older patients (age 65 years or more) and to compare CABG costs for this age group with those for patients less than 65 years of age. METHODS: Direct medical costs were estimated from a sample of 205 older and 202 younger patients with triple-vessel or left main coronary artery disease who underwent isolated CABG at The Toronto Hospital, a tertiary care university-affiliated hospital, between Apr. 1, 1991, and Mar. 31, 1992. Costs are expressed in 1992 Canadian dollars from a third-party payer perspective. RESULTS: The mean costs of CABG in older and younger patients respectively were $16,500 and $15,600 for elective, uncomplicated cases, $23,200 and $19,200 for nonelective, uncomplicated cases, $29,200 and $20,300 for elective, complicated cases, and $33,600 and $23,700 for nonelective, complicated cases. Age remained a significant determinant of costs after adjustment for severity of heart disease and for comorbidity. Between 59% and 91% of the cost difference between older and younger patients was accounted for by higher intensive care unit and ward costs. INTERPRETATION: CABG was more costly in older people, especially in complicated cases, even after an attempt to adjust for severity of disease and comorbidity. Future studies should attempt to identify modifiable factors that contribute to longer intensive care and ward stays for older patients.

Full Text

The Full Text of this article is available as a PDF (136.3 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson G. M., Grumbach K., Luft H. S., Roos L. L., Mustard C., Brook R. Use of coronary artery bypass surgery in the United States and Canada. Influence of age and income. JAMA. 1993 Apr 7;269(13):1661–1666. [PubMed] [Google Scholar]
  2. Anderson G. M., Lomas J. Monitoring the diffusion of a technology: coronary artery bypass surgery in Ontario. Am J Public Health. 1988 Mar;78(3):251–254. doi: 10.2105/ajph.78.3.251. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Anderson G. M., Newhouse J. P., Roos L. L. Hospital care for elderly patients with diseases of the circulatory system. A comparison of hospital use in the United States and Canada. N Engl J Med. 1989 Nov 23;321(21):1443–1448. doi: 10.1056/NEJM198911233212105. [DOI] [PubMed] [Google Scholar]
  4. Arom K. V., Emery R. W., Petersen R. J., Schwartz M. Cost-effectiveness and predictors of early extubation. Ann Thorac Surg. 1995 Jul;60(1):127–132. [PubMed] [Google Scholar]
  5. Black A. J., Roubin G. S., Sutor C., Moe N., Jarboe J. M., Douglas J. S., Jr, King S. B., 3rd Comparative costs of percutaneous transluminal coronary angioplasty and coronary artery bypass grafting in multivessel coronary artery disease. Am J Cardiol. 1988 Oct 1;62(10 Pt 1):809–811. doi: 10.1016/0002-9149(88)91228-3. [DOI] [PubMed] [Google Scholar]
  6. Black N., Langham S., Petticrew M. Trends in the age and sex of patients undergoing coronary revascularisation in the United Kingdom 1987-93. Br Heart J. 1994 Oct;72(4):317–320. doi: 10.1136/hrt.72.4.317. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Cohen D. J., Breall J. A., Ho K. K., Weintraub R. M., Kuntz R. E., Weinstein M. C., Baim D. S. Economics of elective coronary revascularization. Comparison of costs and charges for conventional angioplasty, directional atherectomy, stenting and bypass surgery. J Am Coll Cardiol. 1993 Oct;22(4):1052–1059. doi: 10.1016/0735-1097(93)90415-w. [DOI] [PubMed] [Google Scholar]
  8. Corcoran P. J. Use it or lose it--the hazards of bed rest and inactivity. West J Med. 1991 May;154(5):536–538. [PMC free article] [PubMed] [Google Scholar]
  9. Creditor M. C. Hazards of hospitalization of the elderly. Ann Intern Med. 1993 Feb 1;118(3):219–223. doi: 10.7326/0003-4819-118-3-199302010-00011. [DOI] [PubMed] [Google Scholar]
  10. Disch D. L., O'Connor G. T., Birkmeyer J. D., Olmstead E. M., Levy D. G., Plume S. K. Changes in patients undergoing coronary artery bypass grafting: 1987-1990. Northern New England Cardiovascular Disease Study Group. Ann Thorac Surg. 1994 Feb;57(2):416–423. doi: 10.1016/0003-4975(94)91008-1. [DOI] [PubMed] [Google Scholar]
  11. Dudley R. A., Harrell F. E., Jr, Smith L. R., Mark D. B., Califf R. M., Pryor D. B., Glower D., Lipscomb J., Hlatky M. Comparison of analytic models for estimating the effect of clinical factors on the cost of coronary artery bypass graft surgery. J Clin Epidemiol. 1993 Mar;46(3):261–271. doi: 10.1016/0895-4356(93)90074-b. [DOI] [PubMed] [Google Scholar]
  12. Finkler S. A. The distinction between cost and charges. Ann Intern Med. 1982 Jan;96(1):102–109. doi: 10.7326/0003-4819-96-1-102. [DOI] [PubMed] [Google Scholar]
  13. Frye R. L., Kronmal R., Schaff H. V., Myers W. O., Gersh B. J. Stroke in coronary artery bypass graft surgery: an analysis of the CASS experience. The participants in the Coronary Artery Surgery Study. Int J Cardiol. 1992 Aug;36(2):213–221. doi: 10.1016/0167-5273(92)90009-r. [DOI] [PubMed] [Google Scholar]
  14. Gardner T. J., Horneffer P. J., Manolio T. A., Pearson T. A., Gott V. L., Baumgartner W. A., Borkon A. M., Watkins L., Jr, Reitz B. A. Stroke following coronary artery bypass grafting: a ten-year study. Ann Thorac Surg. 1985 Dec;40(6):574–581. doi: 10.1016/s0003-4975(10)60352-9. [DOI] [PubMed] [Google Scholar]
  15. Geraci J. M., Rosen A. K., Ash A. S., McNiff K. J., Moskowitz M. A. Predicting the occurrence of adverse events after coronary artery bypass surgery. Ann Intern Med. 1993 Jan 1;118(1):18–24. doi: 10.7326/0003-4819-118-1-199301010-00004. [DOI] [PubMed] [Google Scholar]
  16. Harper C. M., Lyles Y. M. Physiology and complications of bed rest. J Am Geriatr Soc. 1988 Nov;36(11):1047–1054. doi: 10.1111/j.1532-5415.1988.tb04375.x. [DOI] [PubMed] [Google Scholar]
  17. Hemenway D., Sherman H., Mudge G. H., Jr, Flatley M., Lindsey N. M., Goldman L. Comparative costs versus symptomatic and employment benefits of medical and surgical treatment of stable angina pectoris. Med Care. 1985 Feb;23(2):133–141. doi: 10.1097/00005650-198502000-00004. [DOI] [PubMed] [Google Scholar]
  18. Hirsch C. H., Sommers L., Olsen A., Mullen L., Winograd C. H. The natural history of functional morbidity in hospitalized older patients. J Am Geriatr Soc. 1990 Dec;38(12):1296–1303. doi: 10.1111/j.1532-5415.1990.tb03451.x. [DOI] [PubMed] [Google Scholar]
  19. Hoenig H. M., Rubenstein L. Z. Hospital-associated deconditioning and dysfunction. J Am Geriatr Soc. 1991 Feb;39(2):220–222. doi: 10.1111/j.1532-5415.1991.tb01632.x. [DOI] [PubMed] [Google Scholar]
  20. Inouye S. K., Wagner D. R., Acampora D., Horwitz R. I., Cooney L. M., Jr, Hurst L. D., Tinetti M. E. A predictive index for functional decline in hospitalized elderly medical patients. J Gen Intern Med. 1993 Dec;8(12):645–652. doi: 10.1007/BF02598279. [DOI] [PubMed] [Google Scholar]
  21. Jones E. L., Weintraub W. S., Craver J. M., Guyton R. A., Cohen C. L. Coronary bypass surgery: is the operation different today? J Thorac Cardiovasc Surg. 1991 Jan;101(1):108–115. [PubMed] [Google Scholar]
  22. Katz N. M., Hannan R. L., Hopkins R. A., Wallace R. B. Cardiac operations in patients aged 70 years and over: mortality, length of stay, and hospital charge. Ann Thorac Surg. 1995 Jul;60(1):96–101. [PubMed] [Google Scholar]
  23. Keon W. J., Menzies S. C., Lay C. M. Cost of coronary artery bypass surgery: a pilot study. Can J Surg. 1985 May;28(3):283–286. [PubMed] [Google Scholar]
  24. Krueger H., Goncalves J. L., Caruth F. M., Hayden R. I. Coronary artery bypass grafting: how much does it cost? CMAJ. 1992 Jan 15;146(2):163–168. [PMC free article] [PubMed] [Google Scholar]
  25. Laupacis A., Labelle R., Goeree R., Cairns J. The cost-effectiveness of routine post myocardial infarction exercise stress testing. Can J Cardiol. 1990 May;6(4):157–163. [PubMed] [Google Scholar]
  26. Lubitz J. D., Gornick M. E., Mentnech R. M., Loop F. D. Rehospitalizations after coronary revascularization among Medicare beneficiaries. Am J Cardiol. 1993 Jul 1;72(1):26–30. doi: 10.1016/0002-9149(93)90213-v. [DOI] [PubMed] [Google Scholar]
  27. Lynn G. M., Stefanko K., Reed J. F., 3rd, Gee W., Nicholas G. Risk factors for stroke after coronary artery bypass. J Thorac Cardiovasc Surg. 1992 Dec;104(6):1518–1523. [PubMed] [Google Scholar]
  28. Mathew J. P., Parks R., Savino J. S., Friedman A. S., Koch C., Mangano D. T., Browner W. S. Atrial fibrillation following coronary artery bypass graft surgery: predictors, outcomes, and resource utilization. MultiCenter Study of Perioperative Ischemia Research Group. JAMA. 1996 Jul 24;276(4):300–306. [PubMed] [Google Scholar]
  29. Naunheim K. S., Fiore A. C., Wadley J. J., McBride L. R., Kanter K. R., Pennington D. G., Barner H. B., Kaiser G. C., Willman V. L. The changing profile of the patient undergoing coronary artery bypass surgery. J Am Coll Cardiol. 1988 Mar;11(3):494–498. doi: 10.1016/0735-1097(88)91522-7. [DOI] [PubMed] [Google Scholar]
  30. Naylor C. D., Ugnat A. M., Weinkauf D., Anderson G. M., Wielgosz A. Coronary artery bypass grafting in Canada: What is its rate of use? Which rate is right? CMAJ. 1992 Mar 15;146(6):851–859. [PMC free article] [PubMed] [Google Scholar]
  31. Newman M. F., Croughwell N. D., Blumenthal J. A., Lowry E., White W. D., Spillane W., Davis R. D., Jr, Glower D. D., Smith L. R., Mahanna E. P. Predictors of cognitive decline after cardiac operation. Ann Thorac Surg. 1995 May;59(5):1326–1330. doi: 10.1016/0003-4975(95)00076-w. [DOI] [PubMed] [Google Scholar]
  32. Palmer R. M. Acute hospital care of the elderly: minimizing the risk of functional decline. Cleve Clin J Med. 1995 Mar-Apr;62(2):117–128. doi: 10.3949/ccjm.62.2.117. [DOI] [PubMed] [Google Scholar]
  33. Peigh P. S., Swartz M. T., Vaca K. J., Lohmann D. P., Naunheim K. S. Effect of advancing age on cost and outcome of coronary artery bypass grafting. Ann Thorac Surg. 1994 Nov;58(5):1362–1367. doi: 10.1016/0003-4975(94)91914-3. [DOI] [PubMed] [Google Scholar]
  34. Peters S., Chagani K., Paddon P., Nair C. Coronary artery bypass surgery in Canada. Health Rep. 1990;2(1):9–26. [PubMed] [Google Scholar]
  35. Peterson E. D., Jollis J. G., Bebchuk J. D., DeLong E. R., Muhlbaier L. H., Mark D. B., Pryor D. B. Changes in mortality after myocardial revascularization in the elderly. The national Medicare experience. Ann Intern Med. 1994 Dec 15;121(12):919–927. doi: 10.7326/0003-4819-121-12-199412150-00003. [DOI] [PubMed] [Google Scholar]
  36. Platt G. H., Svenson L. W., Woodhead S. E. Coronary artery bypass grafting in Alberta from 1984 to 1989. Can J Cardiol. 1993 Sep;9(7):621–624. [PubMed] [Google Scholar]
  37. Radosević K., Schut T. C., van Graft M., de Grooth B. G., Greve J. A flow cytometric study of the membrane potential of natural killer and K562 cells during the cytotoxic process. J Immunol Methods. 1993 May 5;161(1):119–128. doi: 10.1016/0022-1759(93)90203-j. [DOI] [PubMed] [Google Scholar]
  38. Rao V., Christakis G. T., Weisel R. D., Ivanov J., Peniston C. M., Ikonomidis J. S., Shirai T. Risk factors for stroke following coronary bypass surgery. J Card Surg. 1995 Jul;10(4 Suppl):468–474. doi: 10.1111/j.1540-8191.1995.tb00679.x. [DOI] [PubMed] [Google Scholar]
  39. Roberts A. J., Woodhall D. D., Conti C. R., Ellison D. W., Fisher R., Richards C., Marks R. G., Knauf D. G., Alexander J. A. Mortality, morbidity, and cost-accounting related to coronary artery bypass graft surgery in the elderly. Ann Thorac Surg. 1985 May;39(5):426–432. doi: 10.1016/s0003-4975(10)61950-9. [DOI] [PubMed] [Google Scholar]
  40. Rosenfeld K., Luft H. S., Garnick D. W., McPhee S. J. Changes in patient characteristics and surgical outcomes for coronary artery bypass surgery 1972-82. Am J Public Health. 1987 Apr;77(4):498–500. doi: 10.2105/ajph.77.4.498. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Rubin D. B. Estimating causal effects from large data sets using propensity scores. Ann Intern Med. 1997 Oct 15;127(8 Pt 2):757–763. doi: 10.7326/0003-4819-127-8_part_2-199710151-00064. [DOI] [PubMed] [Google Scholar]
  42. Silver G. A. The indomitable spirit. Am J Public Health. 1988 Mar;78(3):237–237. doi: 10.2105/ajph.78.3.237. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. Smith J. M., Rath R., Feldman D. J., Schreiber J. T. Coronary artery bypass grafting in the elderly: changing trends and results. J Cardiovasc Surg (Torino) 1992 Jul-Aug;33(4):468–471. [PubMed] [Google Scholar]
  44. Taylor G. J., Mikell F. L., Moses H. W., Dove J. T., Katholi R. E., Malik S. A., Markwell S. J., Korsmeyer C., Schneider J. A., Wellons H. A. Determinants of hospital charges for coronary artery bypass surgery: the economic consequences of postoperative complications. Am J Cardiol. 1990 Feb 1;65(5):309–313. doi: 10.1016/0002-9149(90)90293-a. [DOI] [PubMed] [Google Scholar]
  45. Tuman K. J., McCarthy R. J., Najafi H., Ivankovich A. D. Differential effects of advanced age on neurologic and cardiac risks of coronary artery operations. J Thorac Cardiovasc Surg. 1992 Dec;104(6):1510–1517. [PubMed] [Google Scholar]
  46. Ugnat A. M., Naylor C. D. Trends in coronary artery bypass grafting in Ontario from 1981 to 1989. CMAJ. 1993 Feb 15;148(4):569–575. [PMC free article] [PubMed] [Google Scholar]
  47. Weintraub W. S., Jones E. L., Craver J., Guyton R., Cohen C. Determinants of prolonged length of hospital stay after coronary bypass surgery. Circulation. 1989 Aug;80(2):276–284. doi: 10.1161/01.cir.80.2.276. [DOI] [PubMed] [Google Scholar]
  48. Yusuf S., Zucker D., Peduzzi P., Fisher L. D., Takaro T., Kennedy J. W., Davis K., Killip T., Passamani E., Norris R. Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration. Lancet. 1994 Aug 27;344(8922):563–570. doi: 10.1016/s0140-6736(94)91963-1. [DOI] [PubMed] [Google Scholar]

Articles from CMAJ: Canadian Medical Association Journal are provided here courtesy of Canadian Medical Association

RESOURCES