Table 1.
Patient characteristics and clinical and hemodynamic severity indices categorized by self‐reported race/ethnicity.
| Race | Non‐Hispanic black | Non‐Black | p value |
|---|---|---|---|
| Total patients (n) | 50 | 60 | |
| Median age (yrs) | 54 [ ± 15] | 50 [ ± 15] | ‐‐ |
| Gender (n) | |||
| M | 13 | 15 | |
| F | 37 | 45 | |
| BMI | 29.5 [ ± 9.8] | 30.1 [ ± 10.8] | ‐‐ |
| PAH classification | ‐‐ | ||
| Idiopathic | 23 | 14 | |
| CTD | 18 | 23 | |
| Portopulmonary | 4 | 17 | |
| HIV‐related | 5 | 0 | |
| CHD | 0 | 6 | |
| mPAP (mm Hg) | 45.6 [ ± 11.3] | 43.9 [ ± 11.8] | 0.43 |
| PAOP (mm Hg) | 11 [ ± 4] | 12 [ ± 5] | 0.43 |
| RA (mm Hg) | 11 [ ± 6] | 9 [ ± 5] | 0.02 |
| CO (L/min) | 4.5 [ ± 1.7] | 5.4 [ ± 2.1] | 0.02 |
| PVR (dynes‐sec/cm5) | 715 [ ± 415] | 587 [ ± 375] | 0.09 |
| 6MWD (meters) | 263 [ ± 84] | 315 [ ± 99] | < 0.01 |
| BNP (pg/mL) | 468 [ ± 631] | 342 [ ± 599] | 0.30 |
| WHO FC (n) | < 0.01 | ||
| I | 1 | 2 | |
| II | 11 | 24 | |
| III | 31 | 33 | |
| IV | 7 | 1 | |
| TR jet velocity | 3.42 [ ± 0.60] | 3.40 [ ± 0.82] | 0.89 |
| RV abnormality (%)* | 38/48 (79%) | 37/55 (67%) | 0.18 |
| TAPSE/PASP | 0.304 [ ± 0.15] | 0.501 [ ± 0.33] | 0.01 |
| GLS | −13.4% [ ± 5.4] | −17.7% [ ± 5.6] | 0.065 |
| Social vulnerability index | 0.94 [ ± 0.07] | 0.86 [ ± 0.13] | < 0.001 |
| Median income ($) | 43407 [ ± 15531] | 61840 [ ± 18876] | < 0.001 |
Note: Baseline characteristics (age, gender, BMI, PAH classification), hemodynamic measurements, clinical severity indices, social vulnerability index, and median annual income are reported for non‐Hispanic Black and non‐Black patients. Values are provided as mean [± standard deviation] or number (%). n indicates number.
Abbreviations: BMI, body mass index; CTD, connective tissue disease; CHD, congenital heart disease; mPAP, mean pulmonary artery pressure; PCWP, pulmonary capillary wedge pressure; RAP, right atrial pressure; CO, cardiac output; PVR, pulmonary vascular resistance; 6MWD, 6 min walk distance; BNP, brain natriuretic peptide; FC, functional class; TR, tricuspid regurgitant; RH, right heart; TAPSE, tricuspid annular plane systolic excursion; PASP, pulmonary artery systolic pressure; GLS, global longitudinal strain; SVI, social vulnerability index.