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Regional reduction of Integrin α8 expression in Hoxa 11/Hoxd 11 double-mutant kidneys. Whole-mount in situ hybridizations with E13.5 mutant and wild-type littermate kidneys. (Top) The more medial positioning of the mutant kidneys, with the posterior poles nearly touching. Part of the dorsal region of the mutant kidney, and the entire ventral region, showed reduced Integrin α8 expression.
