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. 2025 Jul 28;25:377. doi: 10.1186/s12905-025-03930-w

Table 2.

Comparison of demographic and clinical characteristics between ASA negative and ASA positive groups

Variable ASA Negative (n = 81) ASA Positive (n = 33) p
value
Age(year) 29.63 ± 4.93 29.27 ± 5.19 0.731 α
BMI(kg/m2) 29.91 ± 4.45 30.57 ± 5.86 0.519 α
Gravidity 1.00(0.00–2.00) 0.00(0.00–2.00) 0.101 β
Parity 1.00(0.00–2.00) 0.00(0.00–2.00) 0.261 β
Abortion 0.00(0.00–2.00) 0.00(0.00–1.00) 0.449 β
BMI category Normal 11 (13.6%) 5 (15.2%) 0.907 γ
Overweight 33 (40.7%) 12 (36.4%)
Obese 37 (45.7%) 16 (48.5%)
Marital status Married 49 (60.5%) 19 (57.6%) 0.376 γ
Single 16 (19.8%) 10 (30.3%)
Divorced 16 (19.8%) 4 (12.1%)
Working status Working 23 (28.4%) 1 (3.0%) 0.003 γ
Not working 58 (71.6%) 32 (97.0%)
Smoking 29 (35.8%) 19 (57.6%) 0.033 γ
Positive family history for PCOS 12 (14.8%) 15 (45.5%) 0.001 γ
Duration of illness(year) 4.00(0.00–13.00) 3.00(0.00–12.00) 0.883 β
Menstrual irregularity 63 (77.8%) 30 (90.9%) 0.101 γ
Hirsutism 31 (38.3%) 9 (27.3%) 0.264 γ
Weight gain 59 (72.8%) 30 (90.9%) 0.034 γ
Acne 27 (33.3%) 19 (57.6%) 0.017 γ
İnfertility 25 (30.9%) 21 (63.6%) 0.001 γ
Age at first mens 14.46 ± 1.40 13.91 ± 1.40 0.060 α
Total Testosterone (ng/dL) 114.21 ± 12.71 123.27 ± 15.96 0.005 α
DHEAS (µg/dL) 167.91(114.49–247.00) 210.78(101.00–241.25) 0.009 β
Estradiol (pg/mL) 94.86 ± 23.17 118.52 ± 17.40 0.001 α
Prolactin (ng/mL) 14.45 ± 3.25 13.46 ± 4.84 0.286 α
LH (mIU/mL) 10.26 ± 2.21 11.70 ± 1.88 0.001 α
FSH (mIU/mL) 5.49 ± 1.29 4.83 ± 1.09 0.012 α
LH/FSH Ratio 1.85(1.14-4.00) 2.49(1.71–3.38) 0.001 β

α Independent t-test (mean ± SD), β Mann-Whitney U test [median (min-max)], γ chi-square test n (%). BMI: body mass index, ASA: adult separation anxiety, PCOS: polycystic ovary syndrome, DHEAS: dehydroepiandrosterone sulfate, LH: luteinizing hormone, FSH: follicle-stimulating hormone