Table 3.

Naranjo score for drug-induced TEN

Assessment Criteria	Lamotrigine	Oxcarbazepine & Topiramate
Temporal Association	Symptoms appeared 9 days after initiation (+ 2)	Long-term use, no recent dose modification (0)
Dechallenge Outcome	Symptom improvement after discontinuation (+ 1)	Not discontinued (0)
Rechallenge Outcome	Not re-exposed (N/A)	N/A
Established Risk Profile	Strongly associated with SJS/TEN (+ 1)	Low risk of rash (+ 0.5)
Exclusion of Alternative Causes	Negative infectious/autoimmune workup (+ 1)	Long-term tolerance (+ 0)
Total Score	Probable (5 points)	Possible (0.5 points)