Fig. 6.

Title - Cost-effectiveness acceptability Curve (CEAC).

Legend - This figure presents the cost-effectiveness acceptability curve (CEAC) for two strategies: Current Secondary Preventive Therapy (red line) and Current Secondary Preventive Therapy + Colchicine (blue line). The x-axis represents the willingness-to-pay (WTP) threshold in thousand dollars per quality-adjusted life year (QALY), while the y-axis shows the probability of each strategy being cost-effective at a given threshold.

The CEAC demonstrates how the probability of cost-effectiveness changes as the WTP threshold increases. At lower thresholds, Current Secondary Preventive Therapy is the preferred strategy, but as the WTP threshold exceeds approximately $15,000 per QALY, Current Secondary Preventive Therapy + Colchicine becomes increasingly favored and dominates at higher thresholds.

The black square markers denote the cost-effectiveness frontier, highlighting the threshold points where each strategy is most likely to be cost-effective. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)