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. 2025 Jul 28;15:27384. doi: 10.1038/s41598-025-13311-w

Table 4.

Multivariate analysis of factors associated with MACE.

Variables Adjusted HR (95% CI) p-value
*Post-ablation LAVI (/1 mL/m2 increase) 1.02 (1.01–1.04) < 0.001
Post-ablation LARR (/1% increase) 0.98 (0.97–1.004) 0.162
*Age (/1 year increase) 1.05 (1.01–1.09) 0.005
Female 1.04 (0.56–1.93) 0.900
Pre-ablation LVEF (/1% increase) 0.97 (0.95–1.00) 0.051
Arrhythmic recurrence at 3 months post-ablation 0.90 (0.45–1.77) 0.763
*Pre-ablation BNP (/1 pg/mL increase) 1.0001 (1.0002–1.002) 0.017
History of HF hospitalization 1.65 (0.84–3.23) 0.139
Pre-ablation eGFR level (/1 mL/min/1.73m2 increase) 0.99 (0.97–1.01) 0.322
Any structural heart disease 1.07 (0.58–1.97) 0.809

BNP brain natriuretic peptide, CI confidence interval, eGFR estimated glomerular filtration rate, HF heart failure, HR hazard ratio, LARR left atrial reverse remodeling, LAVI left atrial volume index, LVEF left ventricular ejection fraction, MACE major adverse cardiovascular events.

Asterisks indicate statistical significance (*p < 0.05).