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Monoclonal MOG-specific Fab fragments are representative of major Ab specificities in outbred marmosets. Displacement of native, polyclonal serum anti-MOG Abs by M26 (○), M3-8 (□), or a combination of M26 and M3-8 (▵) MOG-specific Fab fragments, and unlabeled serum anti-MOG Abs (▿). Shown here are results obtained with marmoset no. 318-97; identical results were obtained with affinity-purified Abs from 3 additional animals.
